🌿 Kindness - Spreading Goodness And Kindness To The World
  • Kindness
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  • Acts of Kindness
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  • Simple Act of Kindness
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  • Believe in Good
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  • ​Message to the People
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  • Light for the World
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  • 🌿 🌿 🌿 🌿 🌿 🌿 🌿
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  • Lifetime Wisdom
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  • 🌿 🌿 🌿 🌿 🌿 🌿 🌿
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  • The Common Cold
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  • Most Harmful in Food
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  • Fat & Sugar Do Not Mix
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  • The Miracle of Coffee
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  • The Brain on Cannabis
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  • Marijuana Use
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  • 🌿 🌿 🌿 🌿 🌿 🌿 🌿
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  • Save Your Tonsils
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  • Food for Aging
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  • Green for Life
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  • Hot Water Cure
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  • Protect Your Teeth
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  • Why People are Sick
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  • Healing for the Sick
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  • Protect Your Eyesight
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  • Heal Eye Problems
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  • Mucusless Diet
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  • Not Stored in Fridge
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  • Natural Remedies
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  • The Danger of Wireless
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  • Books You Need in Life
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  • AGNI the General
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  • Cancer
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  • Cancer Heals - 48 Hrs.
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  • Dr. Null and Dr. Lodi
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  • Toxic Laundry
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  • Drinking With Meals
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  • 🌿 L O S E W E I G H T
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  • How to Lose Weight
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  • Lose Weight / 2
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  • Pure and Simple / 1
  • Pure and Simple / 2
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  • 🌿 🌿 🌿 🌿 🌿 🌿
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  • Food Combining
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  • Fat and Sugar
  • 80 - 10 - 10 Diet
  • Danger of Sugar & Fat
  • Help for PCOS
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  • 🌿 O I L
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  • Stop Heating Oil
  • Cooking Without Oil
  • Olive Oil is Bad for You
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  • World Health Retreats
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  • 🌿 🌿 🌿 🌿 🌿 🌿
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  • Avoid Natural Flavors
  • GMO Food
  • Glyphosate
  • H2o / Sodium Fluoride
  • Poison of the Century
  • Silent Killer / MSG
  • Sugar / Bitter Truth
  • Sore Throat - Use Zink
  • Vitamin D
  • 5 LOX - Lethal Enzyme
  • What are Prions?
  • Worst Ingredient ...
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  • Funny French Videos
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  • What is GcMAF?
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  • End of Mental Illness
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  • Extremely Dangerous
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  • World's 6 Best Doctors
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  • Autoimmune Disease
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  • Benefits of Oranges
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  • Miracle of Cucumber
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  • DHA Deficiency
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  • Danger of Vinegar
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  • Extremely ​Toxic
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  • What are Lectins?
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  • How to Make Kefir
  • Coconut Kefir
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  • 🌿 🌿 🌿 🌿 🌿 🌿
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  • Global Intoxication
  • Suicide Cult
  • Snitch Culture
  • The Hidden Truth
  • War Against Marriage
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  • What is a Virus?
  • Dr. Lanka - VIRUS
  • Dr. Lenkei - The Virus
  • AN URGENT VIDEO!
  • The mRNA Vaccination
  • This is Not a Vaccine
  • Science
  • The Invisible Rainbow
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  • 🌿 🌿 🌿 🌿 🌿 🌿
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  • 🌿 J U I C I N G
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  • Celery Juice
  • Medical Medium
  • Medical Medium Book
  • The Miracle of Juicing
  • Juicers / Blenders
  • Juicing - Jay Cordich
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  • 🌿 🌿 🌿 🌿 🌿 🌿
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  • Linus Paulig
  • Vitamin C
  • Cancer & Vitamin C
  • Dr. Hoffer's Vitamins
  • 6000 x Vitamin C
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  • Astaxanthin
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  • Truth About Cancer
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  • Danger of PLASTIC
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  • Unsafe at Any Meal
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  • Hybrid Foods
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  • Health Videos
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  • MMS
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  • Coffee /Alcohol / Brain
  • Coffee / Deadly Poison
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  • Coca Cola and Soda
  • The Result of Cooking
  • McVegan Burger
  • Avoid Alzheimer
  • Alzheimer's and Prion
  • Worse Than Cigarettes
  • Everyone is Allergic
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  • Iridology
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  • Uplifting Music
  • The Best of Kuranesh
  • The Habit
  • Friend of the Animals
  • Just a Mother
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  • Bio Superfood
  • Power of Q 96
  • What the Health
  • Bragg Aminos / Poison
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  • Super Nutrition
  • Banana / Miracle Fruit
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  • Cure for Headache
  • Diet for Acne
  • High Doses / Vitamin D
  • Research on Aging
  • Repair Your DNA
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  • Cure for Mental Illness
  • Mental Health
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  • The Story of My Life
  • The Tombstone
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  • Grandfather's Wisdom
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  • 🌿 D I A B E T E S
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  • Reverse Diabetes
  • Nutrition for Diabetes
  • What to Eat / Diabetes
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  • 🌿 B E A U T I E S
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  • Beauty of Character
  • Beauty of Children
  • Beauty of Kindness
  • Beauty of Women
  • The Beauty of Man
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  • Beauty of Animals
  • Beauty of Clouds
  • Beauty of Birds
  • Beauty of Desert
  • Beauty of Macro
  • Beauty of Winter
  • Beauty of Flowers
  • Unique Flowers
  • Poems
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  • 🌿 K I N D N E S S
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  • Kindness & Gratitude
  • Kindness & Swearing
  • Kindness & Generosity
  • Kindness / Individuality
  • Kindness & Happiness
  • Kindness and Freedom
  • Kindness & Love
  • Kindness in SPAIN
  • Kindness Quotations
  • Fairy Magic Songs
  • Just Play a Song
  • No Negative People
  • Paradox of Our Age
  • A Film for Peace
  • A Revolutionary Idea
  • Behind ​Pornography
  • Book of Kindness
  • Letter of Love
  • Libertà
  • Money and People
  • Poverty
  • Prayer for My Children
  • Videos on Kindness
  • Radiation of Kindness
  • Why Walk We Can Fly
  • Who Will Dare to Love
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  • Message of Peace
  • 365 Days for Travelers
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  • Homeless
  • Need or Greed
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  • Courageous Woman
  • Food of Kindness
  • Kindness Only
  • Universal Quotes Facts
  • Signs of the Times
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  • Divorce and Children
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  • 🌿 H A P P I N E S S
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  • Ho'oponopono
  • Key to Happiness
  • Happiness and Peace
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  • Happy Place on Earth
  • Happy Place on Earth 2
  • Trap of Materialism
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  • 🌿 H E A L T H
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  • 🌿 M O V I E S
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  • Our Daily Poison
  • Earthling
  • Food Inc. / Cowspiracy
  • Food Matters
  • Forks Over Knife
  • Health Videos
  • Thrive / Full Movie
  • Origins Movie
  • Powerful Speech
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  • Film About Life
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  • 🌿 C A N C E R
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  • Cure Cancer
  • Cure with Wheatgrass
  • Cancer... / Dr. Circus
  • Cancer Risk / At Home
  • Cancer & Vitamin C
  • Dr. Leonard Caldwel
  • Ginger & Cancer
  • Hot Dog = Cancer
  • Potato Chips
  • Thyme / Chamomile
  • 7 Top Cancer Foods
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  • Truth About Cancer
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  • 🌿 G R A S S / C U R E
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  • Miracle of Wheatgrass
  • 50 Reasons
  • Super Food Living
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  • 🌿 M A G I C A L
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  • 🌿 M A R K U S
  • R O T H K R A N Z
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  • Magical Recipe
  • Incredible P I Z Z A
  • Loose Weight / Markus
  • Heal Your Face
  • Heal Yourself 101
  • Edible Weeds
  • Raw Food Ideas
  • Miracles
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  • 🌿 H O W - T O
  • L O S E - W E I G H T
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  • How to Lose Weight
  • Loose Weight / Markus
  • Raw Food / Works
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  • World Peace Diet
  • The 80 - 10 - 10 Diet
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  • 🌿 W O R S T F O O D
  • 🌿 W H E A T / E T C .
  • G L U T E N F R E E
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  • Bread
  • Gluten Brain
  • Extreme Dangers
  • Food for Faster Aging
  • Is Wheat Poison?
  • Is Quinoa Gluten Free?
  • Is Corn Gluten-Free?
  • Leaky Guts Syndrome
  • Mental Health / Gluten
  • No Starch for Infants
  • Rice / High in Arsenic
  • Wheat Belly
  • Dark Side of Wheat
  • Worst Food # 1
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  • 🌿 R A W - F O O D
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  • Raw Food
  • Fully Raw Videos
  • Green Smoothies
  • Garden Diet
  • Raw Food Recipes
  • Goldenseal
  • Deception / Raw Juice
  • Naked Juice
  • Most Pesticides Food
  • Real Raw Food Canada
  • Tanny Raw
  • 30 x Nutrition
  • 10 Healthiest Fruits
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  • Avoid Acidity
  • Best Papaya
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  • 🌿 G R E E N - T H E
  • M I R A C L E - F O O D
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  • Green Smoothies
  • Green Smoothies / 2
  • Red Malabar Spinach
  • Is Kale a Miracle Food?
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  • 🌿 R E T R E A T S
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  • Puerto Rico - Healing
  • ECUADOR Paradise
  • Garden of Healing
  • Eden Home Resort
  • Raw Retreat Costa Rica
  • Rancho La Puerta
  • Dr. Sebi's Healing
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  • 🌿 C O F F E E
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  • Dr. Amen on Coffee
  • Dangers of Coffee
  • Side Effects of Coffee
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  • 🌿 C A C A O
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  • Dangers of Cacao
  • Cacao / 2
  • Carob
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  • 🌿 S U N L I G H T
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  • Sunlight the Miracle
  • Sungazing
  • Sunlight by Dr. Kime
  • Solar Civilization
  • Sunlight / Sungazing
  • Sabiduria Cosmica
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  • 🌿 M E A T
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  • Meat
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  • Five Poison in Meat
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  • Avoid Some Fish
  • Chicken
  • Food Inc.
  • A Powerful Speech
  • Hot Dog = Cancer
  • Meat of the Future
  • Beyond Vegetarianism
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  • 🌿 F A S T F O O D
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  • Extremely ​Toxic
  • Fast Food
  • Children & Junk Food
  • Fast Food Poison
  • French Fries
  • Is Subway Real Food?
  • McDonald”s Food USA
  • Mockery of Humanity
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  • 🌿 G M O
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  • What is GMO Food?
  • Glyphosate
  • Glyphosate News
  • GMO News
  • GMO and the DNA
  • 20 GMO Food
  • GMO Products
  • 1000 X Toxic
  • Please Wake Up!
  • Against Humanity
  • GMO Bans and Laws
  • GMO Corn
  • GMO & Russia
  • GMO Linked to Gluten
  • Health Ranger
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  • 🌿 A L U M I N U M
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  • Dark Side of Aluminum
  • Aluminum / Autism
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  • 🌿 C O O K W A R E
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  • Aluminum Cookware
  • Cookwares Danger
  • Crock Pots
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  • 🌿 G E O
  • E N G I N E E R I N G
  • C H E M T R A I L
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  • Reasons Behind
  • Geo Engineering / 1
  • Geo Engineering / 2
  • Geo Engineering / 3
  • Complete Theory
  • Climate Control
  • Chemtrail Material
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  • What Chemtrails Are
  • Vaccines / Chemtrails
  • Chemtrail Protection
  • Engineered Drought
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  • 🌿 S O L U T I O N
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  • Solution for Chemtrail
  • Population Control
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  • 🌿 M O R G E L L O N S
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  • Morgellons Disease
  • Morgellons / 2
  • Old Age
  • Harald Kautz - Vella
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  • 🌿 A R T I F I C I A L
  • I N T E L L I G E N C E
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  • Artificial Intelligence
  • Artificial Intelligence II
  • Black Goo
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  • 🌿 R A D I A T I O N
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  • 5G Cell Phone Dangers
  • Radiation
  • Radiation / West Coast
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  • 🌿 O R G A N I C
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  • Go Organic
  • Eating Organic
  • Culinary Nightmares
  • Eating Healthy / Mental
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  • 🌿 A V O C A D O
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  • Miracle of Avocado
  • Avocado / 2
  • Avocado SEED
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  • 🌿 C O C O N U T
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  • Miracle of Coconut
  • For Dental Health / 1
  • For Dental Health / 2
  • Why Palm Sugar?
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  • 🌿 M I R A C L E
  • F O O D
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  • Green Smoothies
  • Miracle of Greens
  • Miracle of Wheatgrass
  • Miracle of Wild Green
  • Is Kale a Miracle Food?
  • Miracle of Alfalfa
  • Miracle Root / Beet
  • Miracle of Cherry
  • Miracle of Fulvic Acid
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  • How to Make Kefir
  • Miracle Goat Milk
  • Miracle of Lemon
  • Walnut
  • 5 "Careful" Super Food
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  • 🌿 B A N A N A
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  • Miracle of Banana
  • Banana / Loose Weight
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  • 🌿 A L O E - V E R A
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  • Aloe Vera
  • Aloe Vera / 2
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  • 🌿 T O B A C C O
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  • Organic Tobacco
  • Cigarette Additives
  • Eating vs. Smoking
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  • 🌿 F R E E B O O K S
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  • Dr. Shelton / Free PDF
  • Books on Health
  • Tissue Cleaning
  • Diet by Design
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  • Anastasia
  • I Ching Book
  • Napoleon Hill
  • The Power of Now
  • The Power of Now / 2
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  • 🌿 H E A L T H
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  • Calm Nerves
  • Diet in Few Words
  • DOLLAR Stores ?
  • Canola Oil / Facts
  • Food for the Eye
  • Mitochondria
  • Moringa / Super Food
  • Natural Cures
  • Organic Sulfur
  • Sunlight
  • The Silent Ecocide
  • 92 Side Effects
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  • I M M U N I Z A T I O N
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  • Immunization
  • History of Medication
  • Untold Horrors
  • Vaccines / Chemtrails
  • Vaccination Via Air
  • Vaxxed
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  • 🌿 S. F L U O R I D E
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  • H2o / Sodium Fluoride
  • Sodium Fluoride / 2
  • Sodium Fluoride / 3
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  • 🌿 W A T E R
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  • Alkaline Water
  • Test for Fluoride
  • H2o Alkalinity
  • H2o Ionizers
  • How to Mineralize H2o
  • Fluoride Toxicity
  • Plastic Bottles & BPA
  • H2O / Empty Stomach
  • What Water to Drink
  • Water & Lemon Juice
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  • 🌿 C O C A - C O L A
  • S O D A S
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  • Coca Cola and Soda
  • Red Bull etc.
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  • 🌿 S U G A R
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  • Sugar / Bitter Truth
  • Aspartame
  • Aspartame Poisoning
  • Cancer Risk to Millions
  • Erythritol / Sugar
  • Honey
  • Maple Sugar
  • Molasses
  • Why Palm Sugar?
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  • 🌿 D E T O X
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  • Liver & Kidney Cleanse
  • Tissue Cleaning
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  • 🌿 A S T H M A
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  • Asthma
  • Breathing
  • Replace Prednison
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  • 🌿 H E A L I N G
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  • Alzheimer, Arthritis / 1
  • Arthritis / 2
  • Food for Inflammation
  • Ear Infection
  • Heartburn
  • Irritable B. Syndrom
  • Prions & Alzheimer
  • Shingles
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  • 🌿 D E N T I S T R Y
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  • Dental Health / 1
  • Dental Health / 2
  • Magnesium for Teeth
  • Root Canal
  • Toxic Teeth
  • What is Wrong
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  • 🌿 D A N G E R S
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  • Dangers of Cocoa
  • Danger of Grapes / 1
  • Dangers of Microwave
  • Dangers of Night Shade
  • Dangers of Salt
  • Potato
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  • Dangers of Soy
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  • Grapefruit/Medication
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  • Onion Toxicity
  • Toxic Garlic
  • 10 Top Poisonous Food
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  • 🌿 M I L K
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  • Truth about Milk
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  • 🌿 T O X I C F O O D
  • A D D I T I V E
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  • Our Daily Poison
  • Toxic Food Additives
  • Toxic Pizza
  • Pesticide in Citrus
  • Poison on Your Platter
  • Toxic Light Bulbs
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  • 🌿 W E L L N E S S
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  • Iridology
  • Maggot Therapy
  • Stool Examination
  • Over 1000
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  • 🌿 C O S M E T I C S
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  • Dangers of Make-Up / 1
  • Dangers of Make-Up / 2
  • Natural Cosmetics
  • Toxic Cosmetics
  • Heal Your Face
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  • 🌿 C H I L D R E N
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  • Dr. Mendelson
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  • 🌿 MENTAL - HEALTH
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  • 🌿 MIRACLE of NIACIN
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  • Dr. D. G. Amen Clinic
  • Niacin / Mental Illness
  • Niacin / Vitamin B3
  • Niacin Deficency
  • Schizophrenia
  • Real Story of Niacin
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  • Lithium Orotate
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  • Anxiety
  • Anxiety / 2
  • Can Autism Be Cured
  • Gut and Mental Illness
  • Heal Depression
  • Help for Mental Illness
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  • Dr. Abram Hoffer
  • Dr. Hoffer's Vitamins
  • Dr. Andrew Saul Videos
  • Shocking Effects
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  • Mental Health / Gluten
  • Mental Health & Wheat
  • Medication Withdrawal
  • List of SSRI Medication
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  • 🌿 V I T A M I N S
  • M I N E R A L S
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  • Ascorbic Acid / Avoid It
  • Calcium Supplement
  • Vitamin C
  • Vitamin K2
  • Vitamin D / Grounded
  • Magnesium / 1
  • Magnesium / 2
  • Niacin / Vitamin B3
  • Niacin Deficency
  • Niacin / Mental Illness
  • Selenium
  • Real Story of Niacin
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  • 🌿 E X E R C I S E
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  • Benefits of Trampoline
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  • 🌿 G A R D E N I N G
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  • Starvation is Over
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  • Back to Eden
  • Better than Organic
  • Organic Gardening
  • Secret of Eldorado
  • $300 Greenhouse
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  • 🌿 G E N E R A L
  • I N F O R M A T I O N
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  • Paul Harvey / 1965
  • Art
  • Charlotte Iserbyt
  • Educational / Hand
  • Free Energy
  • Food Contains Nanite
  • Golden Ratio
  • Fibonacci Numbers
  • How to Tip
  • Home Sweet Home
  • How to Grow Rich
  • Hunza People
  • Ice Cube Effect
  • Kellogg
  • Kundalini Rising
  • Long Hair
  • More Than Reality
  • Sad Story
  • The Universe
  • Valhalla Culture
  • World Toughest Job
  • 8 Toxic People
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  • No More Prednison
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  • 🌿 F L O W E R S
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  • Flowers Unimaginable
  • Rózsa Özön
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  • 🌿 M U S I C
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  • Panflute Collection
  • Around the World
  • Beauty of Music
  • Carlo Gallozzi - Music
  • Child / Anak
  • Encouragement
  • Kitaro - Music
  • Libertà - Italian
  • Lona - Music
  • Michele Ippolito
  • Music
  • Music for Anxiety
  • Music 2 / Beethoven
  • Secret Garden - Music
  • Miel de Booton / Music
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  • Andreea Petcu - Music
  • Michel Pépé
  • Steve McDonald
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  • 🌿 H I S T O R Y
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  • Ancient Mystery
  • Chinese Wisdom
  • Dragonology
  • The Future
  • The Great Controversy
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  • 🌿 I N T E R V I E W S
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  • Simon Parkes
  • Harald Kautz - Vella
  • Harald Kautz - Vella / 2
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  • 🌿 ENTERTAINMENT
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  • Entertaining Videos
  • Humorous
  • Talent Shows
  • Treasures of Info.
  • The Snake
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  • Consciousness
  • Freedom of Speech
  • Law of Attraction
  • Simple Truth Movies
  • 45 Wisdom for Man
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  • Mucusless Diet
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  • 🌿 P R O B I O T I C
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  • Coconut Yoghurt
  • Cultured Food Life
  • Probiotic / BB 536
  • How to / Kombutcha
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  • 🌿 K E F I R
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  • History of Kefir
  • The Value of Kefir
  • How to Make Kefir - 2
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  • Sun Light Lamp
  • Sleeping
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  • Dr. Mercola
  • Green Med Info
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  • Clean Your Arteries
  • Clean the Mercury
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  • Calcium Removal
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  • 🌿 A N T I - A G I N G
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  • Secret of Long Life
  • Anti Aging Diet
  • Elder Action
  • Inflammation of Aging
  • Telomere / Anti Aging
  • Young Again
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  • Monoatomic Gold
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  • Senior Discount
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  • 🌿 MISCELLANEOUS
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  • Age of Treason
  • Articles / Whole Food
  • Chia Seed
  • Contaminated
  • Doctor Yourself . Com
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  • Epson Salt
  • FODMAP Food List
  • For Beautiful Hair
  • Heal Gout Naturally
  • Health Science
  • Iodine
  • Iron Absorption
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  • Miracle Treasure Book
  • Pictures With Meanings
  • Points of Diseases
  • Rice / Tomato / Potato
  • Rife Machine
  • Today's Worst Disease
  • Future Vaccination
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  • 🌿 M I X E D / I N F O
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  • Food Craving
  • Friends
  • Frequency 432 Hz
  • Hydrogen Peroxid
  • Improve Your Vision
  • Improve Your Vision /2
  • Books
  • How to Make Oetmeal
  • STEVIA DANGER
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  • Life Expectancy Test
  • Carl Blechen
  • Never Buy New Battery
  • Something Deadly
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  • 🌿 B E A U T I F U L
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  • Beauty of Trees
  • Beauty of Nature
  • Nature Videos
  • Unique Pictures
  • Unusual Pictures
  • Act of Kindness
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  • How to Stop Bed Bugs
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  • Lou Corona
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  • Anti Inflamatory
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  • Aloe Vera for Cancer
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  • Craiglist Check Scam
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  • Legal Shield
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  • Bentonite Clay
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  • Niner Simeon
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  • Colors
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  • GMO Potatoe Alert
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  • Amazing Result of C60
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  • Target is Humanity
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  • Surviving in Russia
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  • Meridian
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  • Danger of Products
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  • Pelvic Prolapse
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  • Gluten Free Bread
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The Relationship

​Between Vitamin D and Insulin Resistance
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http://articles.mercola.com/sites/articles/archive/
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https://www.chargeplay.com/q/?s=5qvzsp
"The Grounded 2" is the much anticipated sequel to the feature film,
"The Grounded". 


It is about the greatest health rediscovery of all time. 

Stars Apollo 14 astronaut, Dr. Edgar Mitchell and award-winning
​Canadian science broadcaster, 

Dr. David Suziki.
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http://articles.mercola.com/sites/articles/archive
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Introduction to the Concept of Grounding
Internet Health Guru, Dr. Mercola and his colleague, Cardiologist, Dr Stephen Sinatra discuss the latter's first introduction to the concept of Grounding / Earthing as an effective health modality,

while the latter discusses the importance of Vitamin D, which he does not recommend be taken in pill form but with healthy exposure to natural sunlight.

After all, this is how the human body has been naturally synthesizing Vitamin D since the dawn of time! 

Dr. Mercola brings up Vitamin D because while you are outside and Grounding, be it by talking a barefoot walk in a park or on the beach or just laying down in the grass, this will necessitate that you be outside - and this will afford you the opportunity to obtain natural Vitamin D via sunlight. Low Vitamin D levels in your blood are associated with increased mortality.

Both of these most basic and simple of activities - yet, which are also incredibly important to your health, along with a diet of organic, super healthy and detoxifying foods, with recipes from the Gerson Therapy are what saved Dr. Sinatra's son, Step Sinatra from the brink of death. 

Step Sinatra had been a Wall Street trader, surrounded by what his father describes as a "horseshoe" of electronic equipment; mostly old-fashioned TV screens.

Sitting close to one, let alone 20 of those things, is tantamount to getting slammed by a fire hose of untold amounts of dirty electricity (old TV technology uses a beam of electrons to excite the old style screens into producing images encoded within that stream of electricity). Often he had a cellphone in each ear. 

Long story short, Step Sinatra's body's natural EM field literally got "blown out" and dozens of medical specialists and hundreds of thousands of dollars later, he still hadn't been diagnosed, let alone, cured, as this young man's body steadily wasted away, to the point where he got down to an astonishing 78 lbs! 

It was ultimately through his father's discovery of Grounding, that this son, Step finally got on the road to recovery.
​
Vitamin D3

Higher Doses Reduce Risk of Common Health Concerns


By Chris D. Meletis, ND

http://www.vrp.com/bone-and-joint/vitamin-d3-higher-doses-reduce-risk-of-common-health-concerns

Vitamin D3 is one of the most useful nutritional tools we have at our disposal for improving overall health. This vitamin is unique because cholecalciferol (Vitamin D3) is a vitamin derived from 7-dehyrocholesterol; however, Vitamin D3 acquires hormone-like actions when cholecalciferol (Vitamin D3) is converted to 1,25-dihydroxy Vitamin D3 (Calcitriol) by the liver and kidneys.

As a hormone, Calcitriol controls phosphorus, calcium, and bone metabolism and neuromuscular function. Vitamin D3 is the only vitamin the body can manufacture from sunlight (UVB). Yet, with today’s indoor living and the extensive use of sunscreens due to concern about skin cancer, we are now a society with millions of individuals deficient in life-sustaining bone building and immune modulating 1,25-dihydroxy Vitamin D3.

For more than a century, scientists have recognized that Vitamin D3 is involved in bone health. Research has continued to accumulate, documenting Calcitriol’s role in the reduction of the risk of fractures to a significant degree. The latest research, however, shows that 1,25-dihyroxy Vitamin D3 deficiency is linked to a surprising number of other health conditions such as depression, back pain, cancer, both insulin resistance and pre-eclampsia during pregnancy, impaired immunity and macular degeneration.

As it becomes clear that Vitamin D3 plays a wide role in overall health, it’s becoming equally clear that a large percentage of individuals are deficient in this important nutrient, which has hormone-like activity. The fear of skin cancer has stopped many individuals from obtaining beneficial amounts of sunlight.

The skin uses the energy of UVB to convert 7-dehydrocholesterol into Vitamin D3. Even individuals, who venture out into the sun often and use suntan lotion, may be deficient in Vitamin D3.

Furthermore, as we age, we are less equipped to produce sufficient quantities of this vital nutrient. One study found that age-related declines in kidney function may require older people to ingest more Vitamin D3 to maintain the same blood levels as younger people.1

The Recommended Daily Intake (RDI) of Vitamin D3 is set so low those mature individuals who consume this small amount (400 to 600 International Unites (I.U.’s)) are still likely to be deficient if they live north of the Tropic of Cancer or south of the Tropic of Capricorn.

In fact, researchers have discovered that the RDI, which was considered adequate to prevent osteomalacia (a painful bone disease) or rickets, is not high enough to protect against the majority of diseases linked to 1,25-dihyroxy Vitamin D3 deficiency. For example, an analysis of the medical literature found that at least 1,000 to 2,000 IU of Vitamin D3 per day is necessary to reduce the risk of colorectal cancer and that lower doses of Vitamin D3 did not have the same protective effect.2

Researchers Call for Higher Doses

In an editorial in the March 2007 edition of the American Journal of Clinical Nutrition, a prominent group of researchers from leading institutions such as the University of Toronto, Brigham and Women’s Hospital, Tufts University and University Hospital in Zurich, Switzerland, lashed out at the conventional media for its inaccurate reporting of Vitamin D supplementation.3

The researchers wrote, “Almost every time the public media report that Vitamin D nutrition status is too low, or that higher Vitamin D intakes may improve measures of health, the advice that accompanies the report is outdated and thus misleading. Media reports to the public are typically accompanied by a paragraph that approximates the following:

‘Current recommendations from the Institute of Medicine call for 200 IU/day from birth through age 50 years, 400 IU for those aged 51–70 years, and 600 IU for those aged >70 years. Some experts say that optimal amounts are closer to 1,000 IU daily. Until more is known, it is wise not to overdo it.’ The only conclusion that the public can draw from this is to do nothing different from what they have done in the past.”

The researchers point out that supplemental intake of 400 IU per day barely raises blood concentrations of 25(OH)D, which is the circulating Vitamin D metabolite that serves as the most frequently measured indicator of Vitamin D status. To raise 25(OH)D from 50 to 80 nmol/L requires an additional intake of 1,700 IU Vitamin D per day.

The researchers went on to write that, “The balance of the evidence leads to the conclusion that the public health is best served by a recommendation of higher daily intakes of Vitamin D. Relatively simple and low-cost changes, such as increased food fortification or increasing the amount of Vitamin D in Vitamin supplement products, may very well bring about rapid and important reductions in the morbidity associated with low Vitamin D status.”

One of the challenges is the outdated acceptable upper limit for Vitamin D3 consumption, which was set at 2,000 IU. However, researchers point out that more recent studies have shown that 10,000 IU is the safe upper limit.4

Dr. R. Vieth, one of the foremost authorities on Vitamin D3 supplementation, has extensively studied Vitamin D, and lamented the low requirements for Vitamin D3 in a recent issue of the Journal of Nutrition: “Inappropriately low UL [upper limit] values, or guidance values, for Vitamin D have hindered objective clinical research on Vitamin D nutrition; they have hindered our understanding of its role in disease prevention, and restricted the amount of Vitamin D in multivitamins and foods to doses (that are) too low to benefit public health.”5

When examining the medical literature, it becomes clear that Vitamin D3 affects human health in an astonishing number of ways and that not obtaining enough of this important nutrient can leave the door open to developing a number of health conditions.

Depression

Vitamin D3 deficiency is common in older adults and has been implicated in psychiatric and neurologic disorders. For example, in one study of 80 older adults (40 with mild Alzheimer’s disease and 40 nondemented persons), Vitamin D3 deficiency was associated with low mood and with impairment on two of four measures of cognitive performance.6

Back Pain

Musculoskeletal disorders have been linked to Vitamin D3 deficiency in a number of studies. One of the newest studies explored the role that low Vitamin D3 levels play in the development of chronic low back pain in women. Sixty female patients in Egypt complaining of low back pain lasting more than three months were studied. Researchers measured levels of Vitamin D3 in the women with low back pain and compared those levels to those of 20 matched healthy controls.

The study revealed that patients with low back pain had significantly lower Vitamin D3 levels than controls. Low Vitamin D3 levels (25 OHD < 40 ng/ml) were found in 49/60 patients (81 percent) and 12/20 (60 percent) of controls.7

Bone Health

One of the best known and long-established benefits of Vitamin D3 is its ability to improve bone health and the health of the musculoskeletal system. It is well documented that Vitamin D3 deficiency causes osteopenia, precipitates and exacerbates osteoporosis, causes a painful bone disease known as osteomalacia, and exacerbates muscle weakness, which increases the risk of falls and fractures. Vitamin D3 insufficiency may alter the regulatory mechanisms of parathyroid hormone (PTH) and cause a secondary hyperparathyroidism that increases the risk of osteoporosis and fractures.8

Cognitive Enhancement

Scientists are developing a greater appreciation for Vitamin D3’s ability to improve cognition. In a recent study, Vitamin D3 deficient subjects scored worse on mental function tests compared to individuals who had higher levels of the Vitamin.9 The researchers wrote, “In conclusion, the positive, significant correlation between serum 25(OH)D concentration and MMSE [mental state examination scores] in these patients suggests a potential role for Vitamin D in cognitive function of older adults.”

Mu-Talented Nutrient

Vitamin D3 deficiency has been linked to a host of other conditions such as high blood pressure, fibromyalgia, diabetes, multiple sclerosis, rheumatoid arthritis, and an increased risk of pre-eclampsia and insulin resistance during pregnancy.11,15-16 Most recently, low Vitamin D3 levels have been linked to an increased prevalence of early age-related macular degeneration.17

Proper Dosage

In many of my patients, even after consuming 2,000 to 4,000 IU of Vitamin D3 per day, their test results indicate that their Vitamin D3 levels have not increased. These patients needed to consume 8,000 IU of Vitamin D3 per day to achieve proper blood levels of the Vitamin. Patients should, therefore, have their physicians test their serum 1,25-dihyroxy D3 levels to determine the proper level of supplementation required. Testing is very important due to the fact that, in a small number of patients, Vitamin D3 supplementation can raise calcium levels to an excessively high level. I have found this to be especially true in African American patients. Testing for 1,25-dihyroxy Vitamin D3, PTH and calcium blood levels should therefore become a part of every woman’s regular blood work.

Conclusion

A growing number of researchers who have widely studied Vitamin D3 are almost begging the general public to consume more of this important nutrient. Due to Vitamin D3’s high safety profile in doses up to 10,000 IU per day and because of the wide role it plays in our health, consuming 2,000 to 4,000 IU per day of this nutrient at times of the year when sunlight is scarce is a prudent way to improve overall health.

References

1. Vieth R, Ladak Y, Walfish PG. Age-related changes in the 25-hydroxyVitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more Vitamin D. J Clin Endocrinol Metab. 2003 Jan;88(1):185-91.
2. Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M, Newmark HL, Giovannucci E, Wei M, Holick MF. Optimal Vitamin D status for colorectal cancer prevention: a quantitative meta analysis. Am J Prev Med. 2007 Mar;32(3):210-6.
3. Vieth R, Bischoff-Ferrari H, Boucher BJ, Dawson-Hughes B, Garland CF, Heaney RP, Holick MF, Hollis BW, Lamberg-Allardt C, McGrath JJ, Norman AW, Scragg R, Whiting SJ, Willett WC, Zittermann A. The urgent need to recommend an intake of Vitamin D that is effective. American Journal of Clinical Nutrition. March 2007;85(3):649-650.
4. Hathcock JN, Shao A, Vieth R, Heaney R. Risk assessment for Vitamin D. Am J Clin Nutr. 2007 Jan;85(1):6-18.
5. Vieth R. Critique of the considerations for establishing the tolerable upper intake level for Vitamin D: critical need for revision upwards. J Nutr. 2006 Apr;136(4):1117-22.
6. Wilkins CH, Sheline YI, Roe CM, Birge SJ, Morris JC. Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults. Am J Geriatr Psychiatry. 2006 Dec;14(12):1032-40.
7. Lotfi A, Abdel-Nasser AM, Hamdy A, Omran AA, El-Rehany MA. HypoVitaminosis D in female patients with chronic low back pain. Clin Rheumatol. 2007 Mar 22; [Epub ahead of print].
8. Pérez-López FR. Vitamin D and its implications for musculoskeletal health in women: An update. Maturitas. 2007 Jun 28; [Epub ahead of print].
9. Przybelski RJ, Binkley NC. Is Vitamin D important for preserving cognition? A positive correlation of serum 25-hydroxyVitamin D concentration with cognitive function. Arch Biochem Biophys. 2007 Apr 15;460(2):202-5.
10. Grant WB. An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet-B radiation. Cancer. 2002 Mar 15;94(6):1867-75.
11. Lappe J, Travers-Gustafson D, Davies K, Recker R, Heaney R. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. American Journal of Clinical Nutrition. June 8;85(6):1586-1591.
12. Ma Y, et al. Study presented at the 2007 centennial meeting of the American Association for Cancer Research (AACR), April 14 to 18, 2007, Los Angeles.
13. Cannell JJ, Vieth R, Umhau JC, Holick MF, Grant WB, Madronich S, Garland CF, Giovannucci E. Epidemic influenza and Vitamin D. Epidemiol Infect. 2006 Dec;134(6):1129-40.
14. Kurylowicz A, Bednarczuk T, Nauman J. [The influence of Vitamin D deficiency on cancers and autoimmune diseases development.] [Article in Polish] Endokrynol Pol. 2007;58(2):140-152.
15. Bodnar LM, Catov JM, Simhan HN, Holick MF, Powers RW, Roberts JM. Maternal Vitamin D deficiency increases the risk of preeclampsia. J Clin Endocrinol Metab. 2007 May 29; [Epub ahead of print].
16. Maghbooli Z, Hossein-Nezhad A, Karimi F, Shafaei AR, Larijani B. Correlation between Vitamin D(3) deficiency and insulin resistance in pregnancy. Diabetes Metab Res Rev. 2007 Jul 2; [Epub ahead of print].
17. Parekh N, Chappell RJ, Millen AE, Albert DM, Mares JA. Association Between Vitamin D and Age-Related Macular Degeneration in the Third National Health and Nutrition Examination Survey, 1988 Through 1994. Arch Ophthalmol. May 2007;125: 661-669.
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