Coping with Prednisone, Revised and Updated: (*and Other
Cortisone-Related Medicines) Paperback – December 10, 2007
by Eugenia Zukerman (Author), Julie R. Ingelfinger (Author)
4.2 out of 5 stars 90 customer reviews
See all 5 formats and editions
Read more
Cortisone-Related Medicines) Paperback – December 10, 2007
by Eugenia Zukerman (Author), Julie R. Ingelfinger (Author)
4.2 out of 5 stars 90 customer reviews
See all 5 formats and editions
Read more
How it works
When the body is injured, diseased or infected with a pathogen, the cells of the body release cytokines.
Cytokines are protein, hormone-like messenger molecules that allow cells to communicate, altering one another’s function and regulating cell proliferation. In particular, cytokines dictate the strength and targets of inflammatory and immune response.
Cytokines target the area of concern and increase vascularity (pathways for the blood system — allowing the body access to fight and repair), resulting in inflammation.
When we experience joint discomfort, pain, stiffness, loss of mobility or flexibility, one or all of the following are root causes:
Disease, repeated joint stress or repeated joint issues often result in a destructive inflammation cascade:
Managing the inflammation cascade is paramount to reducing pain and effectively repairing the affected joint area. In over 30 clinical trials and studies, FlexNow® with 100% SheaFlex70™ has been proven to modulate the production of cytokines and control the destructive inflammation cascade:
Learn more about Triterpenes: Nature’s Steroids
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Begin Your Flex Now Trial and Start living your best active life today!
Follow Power of Shea
ProvenOver 30 pharmaceutical-standard clinical trials and studies prove FlexNow® with 100% SheaFlex70™ has a statistically significant and clinically meaningful impact on joint care and management. Our experience includes human, double-blind, placebo-controlled university hospital clinical trials. Studies you can trust, by professionals you can trust.
Click here for more. Clinical Studies
Safe & NaturalNo side effects, No allergies, No contraindications. In over 30 clinical trials and studies, and across tens of thousands of consumers using the product, FlexNow® with 100% SheaFlex70™ has produced no adverse effects.
Click here for more. Safe & Natural
SustainableWild-craft harvested and processed in concert with the UN Development Programme. Shea trees grow wild in West Africa, where most shea nuts are sourced. Local villagers collect ripe shea fruit which has fallen to the ground, process a portion for local use and sell the bulk of the shea nuts (actually the pit of the fruit) to our company, food... Purity and Quality: Manufacturing Process
When the body is injured, diseased or infected with a pathogen, the cells of the body release cytokines.
Cytokines are protein, hormone-like messenger molecules that allow cells to communicate, altering one another’s function and regulating cell proliferation. In particular, cytokines dictate the strength and targets of inflammatory and immune response.
Cytokines target the area of concern and increase vascularity (pathways for the blood system — allowing the body access to fight and repair), resulting in inflammation.
When we experience joint discomfort, pain, stiffness, loss of mobility or flexibility, one or all of the following are root causes:
- Micro cartilage tears – breaks in the cartilage matrix result in the bones of the joint to be closer than they should be (it hurts and often limits flexibility);
- Micro bone fissures – during repair by the body, irregular bone structures (often called bone spurs) may result. These irregular bone structures may tear cartilage, and often result in joints ‘grinding’ or ‘catching’;
- Inflammation — driven by cytokine function, inflammation alone decreases flexibility and mobility of the joint, and causes both tenderness and pain.
Disease, repeated joint stress or repeated joint issues often result in a destructive inflammation cascade:
- Cytokines are released; vascularity in the affected area increases
- Inflammation builds in the affected area; pain, tenderness and discomfort are evident
- The body sends bone tissue and cartilage repair elements to the affected joint. The inflammation impedes proper repair:
- Bone spurs and/or hard/dense bone build up, further damaging already weakened and inflamed cartilage
- Inflamed cartilage is challenging for the body to repair properly. As well, repair elements may be challenging to deliver to the inflamed areas, increasing likelihood of additional bone damage
- Additional damage (to the bone and cartilage) occurs through continued use (movement) of the poorly repaired site
- More cytokines are released: cytokine production can multiply 1000 fold when activated
- Inflammation builds further, and the destructive inflammation cascade continues: cytokine release, inflammation, poor repair, movement, additional damage, cytokine release, inflammation, etc
Managing the inflammation cascade is paramount to reducing pain and effectively repairing the affected joint area. In over 30 clinical trials and studies, FlexNow® with 100% SheaFlex70™ has been proven to modulate the production of cytokines and control the destructive inflammation cascade:
- Cytokine management: Reduces cytokine production: IL-6 by 31% and TNF-a by 24%
- Inflammation reduction: Reduces inflammation by 9X
- Bone regulation: Reduces bone destruction (and repair requirement) by almost 10%
- Cartilage retention: Reduces breakdown in cartilage by 44%
- Pain management: Reduces pain by 45%
Learn more about Triterpenes: Nature’s Steroids
Learn more about our Satisfaction Guarantee
Begin Your Flex Now Trial and Start living your best active life today!
Follow Power of Shea
ProvenOver 30 pharmaceutical-standard clinical trials and studies prove FlexNow® with 100% SheaFlex70™ has a statistically significant and clinically meaningful impact on joint care and management. Our experience includes human, double-blind, placebo-controlled university hospital clinical trials. Studies you can trust, by professionals you can trust.
Click here for more. Clinical Studies
Safe & NaturalNo side effects, No allergies, No contraindications. In over 30 clinical trials and studies, and across tens of thousands of consumers using the product, FlexNow® with 100% SheaFlex70™ has produced no adverse effects.
Click here for more. Safe & Natural
SustainableWild-craft harvested and processed in concert with the UN Development Programme. Shea trees grow wild in West Africa, where most shea nuts are sourced. Local villagers collect ripe shea fruit which has fallen to the ground, process a portion for local use and sell the bulk of the shea nuts (actually the pit of the fruit) to our company, food... Purity and Quality: Manufacturing Process
Joint Replacement?
FlexNow with 100% SheaFlex70. Quadruple Joint Action Formula
Patented, all natural and clinically proven to impact all four areas required to realize healthy joint function:
1) Reduce inflammation by 9 times: the swelling and tenderness prevent your joint from healing, naturally and effectively
2) Improve cartilage retention by 44%: more cartilage means a smoothly-operating and pain-free joint
3) Increase bone retention by 10%: micro fractures, splints and spurs hurt – and, they cause cartilage damage
4) Alleviate pain by 45%: now you can live your best active life
Receive a two month's supply (2 Bottles)
MSRP: $89.90 Special Offer: $59.95 / 2 Bottles
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From: [email protected] [mailto:[email protected]]
Steve - unfortunately, our product would not do anything to control or reduce an infection in the lung. FlexNow is indicated for inflammation in the joints.
Best of luck to you,
FlexNow with 100% SheaFlex70. Quadruple Joint Action Formula
Patented, all natural and clinically proven to impact all four areas required to realize healthy joint function:
1) Reduce inflammation by 9 times: the swelling and tenderness prevent your joint from healing, naturally and effectively
2) Improve cartilage retention by 44%: more cartilage means a smoothly-operating and pain-free joint
3) Increase bone retention by 10%: micro fractures, splints and spurs hurt – and, they cause cartilage damage
4) Alleviate pain by 45%: now you can live your best active life
Receive a two month's supply (2 Bottles)
MSRP: $89.90 Special Offer: $59.95 / 2 Bottles
Sales <[email protected]>
From: [email protected] [mailto:[email protected]]
Steve - unfortunately, our product would not do anything to control or reduce an infection in the lung. FlexNow is indicated for inflammation in the joints.
Best of luck to you,
Have you heard of Flex Now?
It' supposed to be "as strong as steroids" but made from Shea nut extract.
http://www.powerofshea.com/
My Holistic doctor recommended it. I'm about to start it soon. I'm trying to get of Pred as well. I'm also going to see another Holistic doc regarding Mck. Jefferies protocol. Dr. Mck. Jefferies did extensive research on steroids and was able to switch patents from Pred to Hydrocortisone. Hydrocortisone is easier to taper off from.
Unfortunately Mck. Jefferies has passed away and a lot of his work is getting lost. He wrote a book on safe uses of cortisols which I read. I have a friend who was treated by his protocol for over 20 years for Crohn's. You can Google Mck. Jefferies. His work is only listed on this doctor's website. Got an appt with him in 2 weeks.
Diagnosed July 2010
flaring as Jan 2010 and now Anemic
As of 5/25/2011 procitis is now pancolitis!!
Pred 40mg started 6/4/2011, 20mg, as of 9/13/2011
LDN 4.5 mg 4/23/2011 / Apriso / Entocort EC
Stopped supplements due to a rash and slowly adding them back / Fen-gre / L-Glutamine / Folic Acid / MegaFood Blood Builder
It' supposed to be "as strong as steroids" but made from Shea nut extract.
http://www.powerofshea.com/
My Holistic doctor recommended it. I'm about to start it soon. I'm trying to get of Pred as well. I'm also going to see another Holistic doc regarding Mck. Jefferies protocol. Dr. Mck. Jefferies did extensive research on steroids and was able to switch patents from Pred to Hydrocortisone. Hydrocortisone is easier to taper off from.
Unfortunately Mck. Jefferies has passed away and a lot of his work is getting lost. He wrote a book on safe uses of cortisols which I read. I have a friend who was treated by his protocol for over 20 years for Crohn's. You can Google Mck. Jefferies. His work is only listed on this doctor's website. Got an appt with him in 2 weeks.
Diagnosed July 2010
flaring as Jan 2010 and now Anemic
As of 5/25/2011 procitis is now pancolitis!!
Pred 40mg started 6/4/2011, 20mg, as of 9/13/2011
LDN 4.5 mg 4/23/2011 / Apriso / Entocort EC
Stopped supplements due to a rash and slowly adding them back / Fen-gre / L-Glutamine / Folic Acid / MegaFood Blood Builder
https://biomediclabs.wordpress.com/2011/03/02/is-there-an-alternative-to-prednisone/
http://www.herbwisdom.com/herb-licorice-root.html
http://www.herbwisdom.com/herb-licorice-root.html
Flex Now Joint Formula 90 Softgels By BSP Pharma
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Your Price:$32.99
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Part Number:858492001001
FlexJoint Formula is the ultimate all natural clinically proven formula for healthy joints. Having the ability to reduce inflammation, improve cartilage retention by 40% and increase bone retention by 10%;
FlexJoint formula offers all the necessary supplements that will keep your joints healthy and strong.
Ask a question.
Your Price:$32.99
Retail Price:$47.99
Your Savings:$15.00(31%)
Shipping: Free
In Stock
Part Number:858492001001
- Clinically proven joint-relief formula
- Improves cartilage retention
- Increases bone retention
- Reduces painful joint inflammation
- Includes Shea Nut Extract
FlexJoint Formula is the ultimate all natural clinically proven formula for healthy joints. Having the ability to reduce inflammation, improve cartilage retention by 40% and increase bone retention by 10%;
FlexJoint formula offers all the necessary supplements that will keep your joints healthy and strong.
The Steroid Curse: Prednisone Vs. Methylprednisolone
http://www.healthcentral.com/rheumatoid-arthritis/c/568286/161613/prednisone/
Leslie Rott Health Guide
Published On: August 02, 2013
http://www.healthcentral.com/rheumatoid-arthritis/c/568286/161613/prednisone/
Leslie Rott Health Guide
- I have always had a love-hate relationship with prednisone.
I don’t like to be on it. I was miserable when I was on it all the time, but not being on it, my pain significantly increased.
I was really stubborn, though, and when I was on prednisone on an “as needed” basis, I probably only took it once a month.
Working from Home with RAHolding down a full-time job can be a challenge when you live with RA. Read these work tips and share your own.
The last time I was at my rheumatologist’s, he suggested going back on steroids full time, but rather than putting me back on prednisone, he suggested that I try methylprednisolone.
He told me that while prednisone is the go-to, default steroid in the United States, methylprednisolone is the default in Europe.
You might think a steroid is a steroid, because that is sort of what I thought, too, but my experience suggests otherwise.
A cursory search of PubMed, using the search term “prednisone” reveals 43,591 results and using the search term “methylprednisolone” reveals 20,165 results. This is particularly telling, I think, that there is almost twice as much information about prednisone as there is about methylprednisolone.
We are all familiar with the weightless feeling that prednisone gives – like I feel like the weight of the whole world is on my shoulders and then I take prednisone and I don’t feel that anymore. But what I have felt and experienced is constant hunger, paranoia, weight gain, the tell-tale moon face – you name it.
The only side effect I have really noticed from the methylprednisolone is that I sweat like a 400-pound man, almost constantly, even when I am sitting down and doing nothing.
Some people may be more familiar with IV Medrol or Solu-Medrol, which is basically the same thing as methylprednisolone, only given by IV instead of orally. I had three days of Solu-Medrol infusions when I first got sick, and I felt great for a month. Granted, when my parents couldn’t find the car when we were leaving the hospital, I sat down in the middle of the parking lot and couldn’t stop laughing like a hyena, but at least I wasn’t feeling any pain.
Unfortunately, I can’t find much information to explain why prednisone is the go-to steroid in America and methylprednisolone is the go-to steroid in other countries.
But what I can say is that my experience with methylprednisolone has been better than the experience I have had with prednisone. I can only speak to my own experience, but if you have had issues with the side-effects of prednisone, it may be worth talking to your doctor to see if you can be put on another type of steroid.
If you have to be on prednisone, I highly recommend that book, “Coping with Prednisone,” which made me feel less crazy about the side effects I was having when I first started taking steroids.
Published On: August 02, 2013
- methylprednisolone >> prednisone... keep hearing that methylprednisolone is better than prednisone as far as efficacy and side effects after making the necessary adjustments for dosage, but when I ask a doctor about it I am told they should be the same.
Methylpednisolons >> Prednisone
... Methylprednisolone is a more "potent" type of corticosteroid. It is very similar to Prednisone, and they are often used interchangeably, but it is not the same thing. Which is "better" is dependent on its use. It may even be a matter of doctor's preference. Corticosteroids all work about the same in the body. The biggest difference is how closely they resemble the "natural" form of cortisol. Dosage is adjusted to attain desired results, and they are ALL interchangeable. The exceptions to interchangeable would be if you are taking other medication with the steroid.- Some antibiotics and blood thinners, for example, work differently with prednisone on board. You can adjust the dosage of Prednisone, or methylprednisolone, to the equivilent of hydrocortisone (more similar to the natural cortisol), or the other cortisol synthetics. 4 mg methylpred = 5 mg prednisone = 20 mg hydrocortisone. One other thing to factor in... There are three classes of these. The short-acting, intermediate acting and long acting. Pred and Methylpred are intermediate acting. Hydrocortisone, is a short acting, and usually requires a twice or more daily dose. Dexamethasone is a long acting and is given in smaller doses and possibly even every other day. All Corticosteroid "rules" apply to any one of them. Don't stop taking it suddenly. Don't use for longer than the doctor orders without re-evaluation, etc. If you have taken it before, you are familiar with the rules and the reasons.
Natural alternatives to prednisone?
Herbal Alternatives to Prednisone
By Robin Reichert
https://www.leaf.tv/articles/herbal-alternatives-to-prednisone/
Prednisone is often prescribed to treat people with rheumatoid arthritis, lupus and asthmatic conditions, and is a steroid that offers fast and powerful anti-inflammatory properties. Prednisone is sometimes prescribed for painful conditions associated with the onset of cancer, as well. The steroid is associated with a number of harmful side effects, however, and some people would prefer using an herbal alternative to avoid the potential side effects associated with steroid use. Scientists are now beginning to reveal highly effective herbal alternatives to prednisone use.
Prednisone Use and Side Effects
Prednisone is a steroid with the ability to stop inflammation from occurring; this medication can be prescribed for the treatment of extreme allergies, skin disorders and rashes, ulcerative colitis, and breathing difficulties. The steroid is indeed powerful as an anti-inflammatory, but the numerous side effects make it a medication that is not good for long term uses. Prednisone can diminish immunological functioning, and the complete course of the medication must be taken exactly as prescribed to reduce the risk of withdrawal symptoms.
If you use prednisone for an extensive period of time, you may suffer from a thinning of the skin, the accumulation of body fat in the waist, back, neck, and facial areas, sexual dysfunctions, and you may bruise with ease. If you are a woman, you may also face potential problems with menstruation when taking prednisone for long periods of time.
Prednisone use is sometimes associated with insomnia, altered moods, the development of unwanted acne, the presence of dry skin, skin discoloring, slower healing of wounds, profuse sweating, vertigo, headaches, abdominal pain and nausea, and/or bloating. Finally, the extended use of prednisone is sometimes associated with severe depression, changes in personality, hypertension, and fluid retention.
Lig-Zhi, Ku-Shen, and Gan-Cao Herbal Combo
Recent testing conducted at the Weifan Asthma Hospital located in China, as well as studies conducted in New York at the Mount Sinai School of Medicine, have unveiled Chinese herbs that can be utilized as an alternative to prednisone and other steroid medications.
Researchers combined three distinct herbal extracts of Chinese origin identified as Lig-Zhi, Ku-Shen and Gan-Cao, which can be combined to offer the same positive effects of prednisone without the same negative side effects associated with steroid use.
Patients were given 20 grams of Ling-Zhi, 3 grams of Gan-Cao, and 9 grams of Ku-Shen per day, which offered improved lung functioning in asthmatics without any side effects. Once the asthmatic condition passes, you can cease using the combination of non-steroidal herbs.
These herbs can be purchased online or at a health store specializing in the sale of herbs.
Dong Quai
Dong Quai is an excellent alternative to prednisone being prescribed for pain control. Dong Quai offers natural anti-inflammatory properties as well as immunological boosting attributes.
This herb also offers antispasmodic properties, and can be used for the treatment of pain in the abdominal region, arthritic conditions and for the treatment of headaches.
Dong Quai can be safely consumed on a daily basis: the herb can be consumed at a dosage of two to four 530 mg capsules every day. Capsules should be consumed with a meal for ease of digestion, and pregnant and/or breast-feeding women should refrain from using the product.
Dong Quai is sold in some drug stores, in health stores, and it is available online.
By Robin Reichert
https://www.leaf.tv/articles/herbal-alternatives-to-prednisone/
Prednisone is often prescribed to treat people with rheumatoid arthritis, lupus and asthmatic conditions, and is a steroid that offers fast and powerful anti-inflammatory properties. Prednisone is sometimes prescribed for painful conditions associated with the onset of cancer, as well. The steroid is associated with a number of harmful side effects, however, and some people would prefer using an herbal alternative to avoid the potential side effects associated with steroid use. Scientists are now beginning to reveal highly effective herbal alternatives to prednisone use.
Prednisone Use and Side Effects
Prednisone is a steroid with the ability to stop inflammation from occurring; this medication can be prescribed for the treatment of extreme allergies, skin disorders and rashes, ulcerative colitis, and breathing difficulties. The steroid is indeed powerful as an anti-inflammatory, but the numerous side effects make it a medication that is not good for long term uses. Prednisone can diminish immunological functioning, and the complete course of the medication must be taken exactly as prescribed to reduce the risk of withdrawal symptoms.
If you use prednisone for an extensive period of time, you may suffer from a thinning of the skin, the accumulation of body fat in the waist, back, neck, and facial areas, sexual dysfunctions, and you may bruise with ease. If you are a woman, you may also face potential problems with menstruation when taking prednisone for long periods of time.
Prednisone use is sometimes associated with insomnia, altered moods, the development of unwanted acne, the presence of dry skin, skin discoloring, slower healing of wounds, profuse sweating, vertigo, headaches, abdominal pain and nausea, and/or bloating. Finally, the extended use of prednisone is sometimes associated with severe depression, changes in personality, hypertension, and fluid retention.
Lig-Zhi, Ku-Shen, and Gan-Cao Herbal Combo
Recent testing conducted at the Weifan Asthma Hospital located in China, as well as studies conducted in New York at the Mount Sinai School of Medicine, have unveiled Chinese herbs that can be utilized as an alternative to prednisone and other steroid medications.
Researchers combined three distinct herbal extracts of Chinese origin identified as Lig-Zhi, Ku-Shen and Gan-Cao, which can be combined to offer the same positive effects of prednisone without the same negative side effects associated with steroid use.
Patients were given 20 grams of Ling-Zhi, 3 grams of Gan-Cao, and 9 grams of Ku-Shen per day, which offered improved lung functioning in asthmatics without any side effects. Once the asthmatic condition passes, you can cease using the combination of non-steroidal herbs.
These herbs can be purchased online or at a health store specializing in the sale of herbs.
Dong Quai
Dong Quai is an excellent alternative to prednisone being prescribed for pain control. Dong Quai offers natural anti-inflammatory properties as well as immunological boosting attributes.
This herb also offers antispasmodic properties, and can be used for the treatment of pain in the abdominal region, arthritic conditions and for the treatment of headaches.
Dong Quai can be safely consumed on a daily basis: the herb can be consumed at a dosage of two to four 530 mg capsules every day. Capsules should be consumed with a meal for ease of digestion, and pregnant and/or breast-feeding women should refrain from using the product.
Dong Quai is sold in some drug stores, in health stores, and it is available online.
Natural alternatives to prednisone?
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Natural alternatives to prednisone??
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Bacon Girl
Veteran Member
Date Joined May 2011
Total Posts : 5399
Posted 9/30/2011 8:41 PM (GMT -6)
i am trying to get off of prednisone and as i taper, i'd like to take something that mimics prednisone's effects without it being a drug. i figure this has to be some kind of anti-inflammatory. any thoughts or suggestions would be great. after most of the spring and summer trying the herbal route, i still have some turmeric and NAG left over.
Joanna
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beachlife
Regular Member
Date Joined Feb 2009
Total Posts : 473
Posted 10/1/2011 2:35 AM (GMT -6)
not a replacement for Prednisone in any sense, but ginger and mint both have nice healing/anti-inflammatory effects. Mint Tea from Starbucks REALLY helped me out just this past weekend in Mexico when I had really bad pain, worst I've had in 2 years. But , Prednisone is a steroid, it's strong and does its job, sadly with side affects :-( Been there, done that.
You mentioned herbal route, have you thought about a naturopath dr, or traditional chinese medicine(TCM) Doctor. Contact some of your local holistic centers, they can point you in the right direction. Before I go on Prednisone again I'll probably fly to see a Ayurvedic GI specialist recommended by a friend
http://lifewithcolitis.blogspot.com/
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bhb5764
Joanna,
I am in the exact same position as you are. I'm currently weaning off prednisone and I have added in the following supplements in the hope of not re-flaring (I am also continuing on Humira, Asacol, and Rowasa, VSL#3): tumeric, slippery elm, boswellia, and ginger, all of which are supposed to have anti-inflammatory properties. For guidance on dosage, I looked at the University of Maryland's site on alternative medicines for UC: http://www.umm.edu/altmed/articles/ulcerative-colitis-002684.htm. Also, there are many people on this forum that have had good results from tumeric and boswellia, so you can get some more info by searching those herbs.
I did actually go to see a doctor who is an MD but practices only homeopathic medicine (It was VERY expensive b/c she doesn't accept insurance, but I am pretty desperate to get off prednisone and prevent the next flare). I wasn't too happy with the overall experience because I felt that she was not taking into account the autoimmune and inflammatory nature of UC and was basically recommending supplements that would be better suited for someone with IBS (however, I could totally be wrong. I just was surprised that nothing she recommended had any of the herbs listed above in them). In any case, here are the supplements she recommended--I haven't taken them yet but will try them if I start to flare again on the taper: GlutAloeMine (brand name), Gastrex (brand name made by Standard Process), Gut Flora Complex (made by MediHerb), and Zypan (brand name made by Standard Process).
Hope you get off prednisone soon!
Bridget
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seasons21
I am tapering also. The whole time I've been on Prednisone my naturopath has me taking liquid licorice root. He was adamant that I take it. He said it would support my adrenals. I was doing 1/4 tsp once in am and once around noon. He wants me to increase it my 1/4 tsp as I taper. It is also anti inflammatory and he said it would keep the Prednisone in me longer so I would need less.
I pray we both get off. BTW are you still having any sxs? I am not completely sx free and I am not on maintenace meds. Too scared to do immunos yet. We'll see. I pray I'm not at square one again.
M
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suebear
Just remember that natural does not mean safe or healthier than Rxs. Most of our Rx drugs evolved from plants. Differences are in rigorous testing. I'm not opposed to herbal and alternative treatments, did them myself, but don't be fooled into thinking they are safer.
Sue
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journey2health
Are you taking a probiotic? Turmeric is also recommended as an anti-inflammatory though it did nothing for me.
In remission (yippee!)--pancolitis since 8/09. Asacol 3200 mg. Canasa or Rowasa daily, Probiotic -RenewLife Ultimate Flora Critical Care, vitamins, calcium, l-acetyl carnitine. Limit dairy, red meat, citrus, sugar, no alcohol. Bipolar/anxiety/depression: lamictal 200 mg, Lexapro 10 mg; wellbutrin 150 mg, Sleep-(ZMA) zinc-magnesium-B6, occasional Zyprexa 2.5 mg.
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beachlife
interesting on the licorice root.
One of the herbs in my herbal tea is "radix glycyrrhizae (Liquorice)"
Blogging UC:
http://lifewithcolitis.blogspot.com/
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Bacon Girl
I haven't heard about licorice root either. i will look into this. i have seen two naturopathic doctors this summer. the one i really liked but the other one's methods landed me in the hospital in august. i tried her program for 3 days and got very sick.
i just started VSL last week. it has helped a lot with my bloating. i've been on 15 mg for a while now and would like to taper but i'm just nervous. the last time i tapered to 10mg i started getting cramps again.
Joanna
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Bacon Girl
http://www.herbwisdom.com/herb-licorice-root.html
i found this good website about it. apparently, licorice root helps prevent the breakdown of the adrenal hormones (this happens when we take prednisone) so our natural supply is more available to the body. it also helps heal ulcers, inflammation, and spasms of the digestive tract.
i just got a gift card for my favorite health store so i'll look for this extract when i go in.
Joanna
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aguywithuc
Veteran Member
All licorice does is provide an inhibitor to the enzyme that breaks down cortisol so that it circulates longer. I guess that 'supports' adrenals but not how I would phrase it. I have bought bottles of the extract when coming of prednisone. You need to read up on it and time it with your natural cortisol production to extend your natural coritisol because what it really 'support's is your plunging artificial cortisol ( predisone ). I know this space well as I have had adrenal shock from plunging too quickly.
Good luck
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stereofidelic89
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seasons21
Veteran Member
Date Joined Aug 2004
Total Posts : 633
Posted 10/1/2011 8:12 PM (GMT -6)
I'm just letting you know what I"m doing to support my adrenals while on Prednisone. I don't usually take anything without his ok. I really like my ND and I do trust him. He if very knowledgable and he is very particular about the quality of the supplements he suggests. If you are considering taking it, it is good to have someone monitor you.
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Peace&Harmony
Have you heard of Flex Now? It' supposed to be "as strong as steroids" but made from Shea nut extract. http://www.powerofshea.com/
My Holistic doctor recommended it. I'm about to start it soon. I'm trying to get of Pred as well. I'm also going to see another Holistic doc regarding Mck. Jefferies protocol. Dr. Mck. Jefferies did extensive research on steroids and was able to switch patents from Pred to Hydrocortisone. Hydrocortisone is easier to taper off from.
Unfortunately Mck. Jefferies has passed away and a lot of his work is getting lost. He wrote a book on safe uses of cortisols which I read. I have a friend who was treated by his protocol for over 20 years for Crohn's. You can Google Mck. Jefferies. His work is only listed on this doctor's website.
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MustLoveDogs
Regular Member
Date Joined Jan 2009
Total Posts : 394
Posted 10/1/2011 10:11 PM (GMT -6)
There is a homeopathic version of prednisone, but it is extremely difficult to get. I took my daughter to a naturopath once but she wouldn't prescribe it. Ironically it is used for dogs quite often! Good luck
13 yr old daughter diagnosed UC 12/08
Just spent 8 days in Hospital due to flare & back on Pred :(
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greenenergy
New Member
Date Joined Oct 2009
Total Posts : 18
Posted 10/2/2011 8:46 AM (GMT -6)
Slippery Elm is very soothing to the gut. There's also the others mentioned. I found MSM to be a good anti-inflammatory but it can sometimes cause diarrhea at high doses so need to start at a low dose and build up.
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Granwest
New Member
Date Joined Jul 2013
Total Posts : 1
Posted 7/29/2013 12:49 PM (GMT -6)
licorice is one to be very vary of though - if you have high blood pressure as it will cause it to go high even while taking medication. But will be trying some of the above alternatives as have just started taking prednisone for respiratory probs.
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Natural alternatives to prednisone??
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Bacon Girl
Veteran Member
Date Joined May 2011
Total Posts : 5399
Posted 9/30/2011 8:41 PM (GMT -6)
i am trying to get off of prednisone and as i taper, i'd like to take something that mimics prednisone's effects without it being a drug. i figure this has to be some kind of anti-inflammatory. any thoughts or suggestions would be great. after most of the spring and summer trying the herbal route, i still have some turmeric and NAG left over.
Joanna
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beachlife
Regular Member
Date Joined Feb 2009
Total Posts : 473
Posted 10/1/2011 2:35 AM (GMT -6)
not a replacement for Prednisone in any sense, but ginger and mint both have nice healing/anti-inflammatory effects. Mint Tea from Starbucks REALLY helped me out just this past weekend in Mexico when I had really bad pain, worst I've had in 2 years. But , Prednisone is a steroid, it's strong and does its job, sadly with side affects :-( Been there, done that.
You mentioned herbal route, have you thought about a naturopath dr, or traditional chinese medicine(TCM) Doctor. Contact some of your local holistic centers, they can point you in the right direction. Before I go on Prednisone again I'll probably fly to see a Ayurvedic GI specialist recommended by a friend
http://lifewithcolitis.blogspot.com/
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bhb5764
Joanna,
I am in the exact same position as you are. I'm currently weaning off prednisone and I have added in the following supplements in the hope of not re-flaring (I am also continuing on Humira, Asacol, and Rowasa, VSL#3): tumeric, slippery elm, boswellia, and ginger, all of which are supposed to have anti-inflammatory properties. For guidance on dosage, I looked at the University of Maryland's site on alternative medicines for UC: http://www.umm.edu/altmed/articles/ulcerative-colitis-002684.htm. Also, there are many people on this forum that have had good results from tumeric and boswellia, so you can get some more info by searching those herbs.
I did actually go to see a doctor who is an MD but practices only homeopathic medicine (It was VERY expensive b/c she doesn't accept insurance, but I am pretty desperate to get off prednisone and prevent the next flare). I wasn't too happy with the overall experience because I felt that she was not taking into account the autoimmune and inflammatory nature of UC and was basically recommending supplements that would be better suited for someone with IBS (however, I could totally be wrong. I just was surprised that nothing she recommended had any of the herbs listed above in them). In any case, here are the supplements she recommended--I haven't taken them yet but will try them if I start to flare again on the taper: GlutAloeMine (brand name), Gastrex (brand name made by Standard Process), Gut Flora Complex (made by MediHerb), and Zypan (brand name made by Standard Process).
Hope you get off prednisone soon!
Bridget
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seasons21
I am tapering also. The whole time I've been on Prednisone my naturopath has me taking liquid licorice root. He was adamant that I take it. He said it would support my adrenals. I was doing 1/4 tsp once in am and once around noon. He wants me to increase it my 1/4 tsp as I taper. It is also anti inflammatory and he said it would keep the Prednisone in me longer so I would need less.
I pray we both get off. BTW are you still having any sxs? I am not completely sx free and I am not on maintenace meds. Too scared to do immunos yet. We'll see. I pray I'm not at square one again.
M
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suebear
Just remember that natural does not mean safe or healthier than Rxs. Most of our Rx drugs evolved from plants. Differences are in rigorous testing. I'm not opposed to herbal and alternative treatments, did them myself, but don't be fooled into thinking they are safer.
Sue
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journey2health
Are you taking a probiotic? Turmeric is also recommended as an anti-inflammatory though it did nothing for me.
In remission (yippee!)--pancolitis since 8/09. Asacol 3200 mg. Canasa or Rowasa daily, Probiotic -RenewLife Ultimate Flora Critical Care, vitamins, calcium, l-acetyl carnitine. Limit dairy, red meat, citrus, sugar, no alcohol. Bipolar/anxiety/depression: lamictal 200 mg, Lexapro 10 mg; wellbutrin 150 mg, Sleep-(ZMA) zinc-magnesium-B6, occasional Zyprexa 2.5 mg.
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beachlife
interesting on the licorice root.
One of the herbs in my herbal tea is "radix glycyrrhizae (Liquorice)"
Blogging UC:
http://lifewithcolitis.blogspot.com/
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Bacon Girl
I haven't heard about licorice root either. i will look into this. i have seen two naturopathic doctors this summer. the one i really liked but the other one's methods landed me in the hospital in august. i tried her program for 3 days and got very sick.
i just started VSL last week. it has helped a lot with my bloating. i've been on 15 mg for a while now and would like to taper but i'm just nervous. the last time i tapered to 10mg i started getting cramps again.
Joanna
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Bacon Girl
http://www.herbwisdom.com/herb-licorice-root.html
i found this good website about it. apparently, licorice root helps prevent the breakdown of the adrenal hormones (this happens when we take prednisone) so our natural supply is more available to the body. it also helps heal ulcers, inflammation, and spasms of the digestive tract.
i just got a gift card for my favorite health store so i'll look for this extract when i go in.
Joanna
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aguywithuc
Veteran Member
All licorice does is provide an inhibitor to the enzyme that breaks down cortisol so that it circulates longer. I guess that 'supports' adrenals but not how I would phrase it. I have bought bottles of the extract when coming of prednisone. You need to read up on it and time it with your natural cortisol production to extend your natural coritisol because what it really 'support's is your plunging artificial cortisol ( predisone ). I know this space well as I have had adrenal shock from plunging too quickly.
Good luck
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stereofidelic89
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seasons21
Veteran Member
Date Joined Aug 2004
Total Posts : 633
Posted 10/1/2011 8:12 PM (GMT -6)
I'm just letting you know what I"m doing to support my adrenals while on Prednisone. I don't usually take anything without his ok. I really like my ND and I do trust him. He if very knowledgable and he is very particular about the quality of the supplements he suggests. If you are considering taking it, it is good to have someone monitor you.
Back to Top
Peace&Harmony
Have you heard of Flex Now? It' supposed to be "as strong as steroids" but made from Shea nut extract. http://www.powerofshea.com/
My Holistic doctor recommended it. I'm about to start it soon. I'm trying to get of Pred as well. I'm also going to see another Holistic doc regarding Mck. Jefferies protocol. Dr. Mck. Jefferies did extensive research on steroids and was able to switch patents from Pred to Hydrocortisone. Hydrocortisone is easier to taper off from.
Unfortunately Mck. Jefferies has passed away and a lot of his work is getting lost. He wrote a book on safe uses of cortisols which I read. I have a friend who was treated by his protocol for over 20 years for Crohn's. You can Google Mck. Jefferies. His work is only listed on this doctor's website.
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MustLoveDogs
Regular Member
Date Joined Jan 2009
Total Posts : 394
Posted 10/1/2011 10:11 PM (GMT -6)
There is a homeopathic version of prednisone, but it is extremely difficult to get. I took my daughter to a naturopath once but she wouldn't prescribe it. Ironically it is used for dogs quite often! Good luck
13 yr old daughter diagnosed UC 12/08
Just spent 8 days in Hospital due to flare & back on Pred :(
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greenenergy
New Member
Date Joined Oct 2009
Total Posts : 18
Posted 10/2/2011 8:46 AM (GMT -6)
Slippery Elm is very soothing to the gut. There's also the others mentioned. I found MSM to be a good anti-inflammatory but it can sometimes cause diarrhea at high doses so need to start at a low dose and build up.
Back to Top
Granwest
New Member
Date Joined Jul 2013
Total Posts : 1
Posted 7/29/2013 12:49 PM (GMT -6)
licorice is one to be very vary of though - if you have high blood pressure as it will cause it to go high even while taking medication. But will be trying some of the above alternatives as have just started taking prednisone for respiratory probs.
natural alternatives to prednisone??
Forum Rules | Moderators | Password Help
HealingWell.com Forum > Diseases & Conditions > Ulcerative Colitis > natural alternatives to prednisone??
Select A Location****** Top of the Forum ******==== General Information ====AnnouncementsFrequently Asked QuestionsForum Rules & Guidelines==== Diseases & Conditions ====Allergies & AsthmaAlzheimer's DiseaseAnxiety - Panic DisordersBipolar DisorderBreast CancerCeliac DiseaseChronic Fatigue SyndromeChronic PainCrohn's DiseaseCystic FibrosisDepressionDiabetesEpilepsyFibromyalgiaGERD - HeartburnHeart & Cardiovascular DiseaseHepatitisIrritable Bowel SyndromeKidney Diseases & DisordersLupusLyme DiseaseMigraine - HeadacheMultiple SclerosisOsteoarthritisOstomiesParkinson's DiseaseProstate CancerPsoriasisRheumatoid ArthritisSjogren's SyndromeThyroid DisordersUlcerative Colitis
[ << Previous Thread | Next Thread >> ]
Bacon Girl
i am trying to get off of prednisone and as i taper, i'd like to take something that mimics prednisone's effects without it being a drug. i figure this has to be some kind of anti-inflammatory. any thoughts or suggestions would be great. after most of the spring and summer trying the herbal route, i still have some turmeric and NAG left over.
Joanna
Age:21
severe pancolitis
medications: 15 mg prednisone, 50 mg 6mp, and remicade
vitamins and minerals: VSL, 1 multivitamin, calcium, vit D, and zinc citrate.
remicade infusion aug 29, 2011, sept 12, 2011, and next one is oct. 10.
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beachlife
not a replacement for Prednisone in any sense, but ginger and mint both have nice healing/anti-inflammatory effects. Mint Tea from Starbucks REALLY helped me out just this past weekend in Mexico when I had really bad pain, worst I've had in 2 years. But , Prednisone is a steroid, it's strong and does its job, sadly with side affects :-( Been there, done that.
You mentioned herbal route, have you thought about a naturopath dr, or traditional chinese medicine(TCM) Doctor. Contact some of your local holistic centers, they can point you in the right direction. Before I go on Prednisone again I'll probably fly to see a Ayurvedic GI specialist recommended by a friend
good luck, I know prednisone isn't fun, hopefully you at least have good energy!!
Blogging UC:
http://lifewithcolitis.blogspot.com/
Vegan/Pescatarian - ish, , Yoga, Traditional Chinese Medicine
'00 - UC - Proctitis
Lialda 4x/day(2+2)
Testim 1% - Testosterone
Vit D 50,000 ICU/week
VSL#3
Back to Top
bhb5764
Regular Member
Date Joined Nov 2009
Total Posts : 105
Posted 10/1/2011 6:44 AM (GMT -6)
Joanna,
I am in the exact same position as you are. I'm currently weaning off prednisone and I have added in the following supplements in the hope of not re-flaring (I am also continuing on Humira, Asacol, and Rowasa, VSL#3): tumeric, slippery elm, boswellia, and ginger, all of which are supposed to have anti-inflammatory properties. For guidance on dosage, I looked at the University of Maryland's site on alternative medicines for UC: http://www.umm.edu/altmed/articles/ulcerative-colitis-002684.htm. Also, there are many people on this forum that have had good results from tumeric and boswellia, so you can get some more info by searching those herbs.
I did actually go to see a doctor who is an MD but practices only homeopathic medicine (It was VERY expensive b/c she doesn't accept insurance, but I am pretty desperate to get off prednisone and prevent the next flare). I wasn't too happy with the overall experience because I felt that she was not taking into account the autoimmune and inflammatory nature of UC and was basically recommending supplements that would be better suited for someone with IBS (however, I could totally be wrong. I just was surprised that nothing she recommended had any of the herbs listed above in them). In any case, here are the supplements she recommended--I haven't taken them yet but will try them if I start to flare again on the taper: GlutAloeMine (brand name), Gastrex (brand name made by Standard Process), Gut Flora Complex (made by MediHerb), and Zypan (brand name made by Standard Process).
Hope you get off prednisone soon!
Bridget
11 years of UC
Currently taking: Asacol, Rowasa, Canasa, Humira (started 4/11), tumeric, ginger, boswellia, slippery elm, VSL#3
Discontinued: Remicade
Back to Top
seasons21
Veteran Member
Date Joined Aug 2004
Total Posts : 633
Posted 10/1/2011 8:38 AM (GMT -6)
I am tapering also. The whole time I've been on Prednisone my naturopath has me taking liquid licorice root. He was adamant that I take it. He said it would support my adrenals. I was doing 1/4 tsp once in am and once around noon. He wants me to increase it my 1/4 tsp as I taper. It is also anti inflammatory and he said it would keep the Prednisone in me longer so I would need less.
I pray we both get off. BTW are you still having any sxs? I am not completely sx free and I am not on maintenace meds. Too scared to do immunos yet. We'll see. I pray I'm not at square one again.
Back to Top
suebear
Forum Moderator
Date Joined Feb 2006
Total Posts : 5621
Posted 10/1/2011 9:31 AM (GMT -6)
Just remember that natural does not mean safe or healthier than Rxs. Most of our Rx drugs evolved from plants. Differences are in rigorous testing. I'm not opposed to herbal and alternative treatments, did them myself, but don't be fooled into thinking they are safer.
Sue
Back to Top
journey2health
Veteran Member
Date Joined Oct 2009
Total Posts : 2787
Posted 10/1/2011 9:49 AM (GMT -6)
Are you taking a probiotic? Turmeric is also recommended as an anti-inflammatory though it did nothing for me.
In remission (yippee!)--pancolitis since 8/09. Asacol 3200 mg. Canasa or Rowasa daily, Probiotic -RenewLife Ultimate Flora Critical Care, vitamins, calcium, l-acetyl carnitine. Limit dairy, red meat, citrus, sugar, no alcohol. Bipolar/anxiety/depression: lamictal 200 mg, Lexapro 10 mg; wellbutrin 150 mg, Sleep-(ZMA) zinc-magnesium-B6, occasional Zyprexa 2.5 mg.
Back to Top
beachlife
Regular Member
Date Joined Feb 2009
Total Posts : 473
Posted 10/1/2011 10:52 AM (GMT -6)
interesting on the licorice root. One of the herbs in my herbal tea is "radix glycyrrhizae (Liquorice)"
Blogging UC:
http://lifewithcolitis.blogspot.com/
Vegan/Pescatarian - ish, , Yoga, Traditional Chinese Medicine
'00 - UC - Proctitis
Lialda 4x/day(2+2)
Testim 1% - Testosterone
Vit D 50,000 ICU/week
VSL#3
Back to Top
Bacon Girl
Veteran Member
Date Joined May 2011
Total Posts : 5399
Posted 10/1/2011 12:39 PM (GMT -6)
yeah, i haven't heard about licorice root either. i will look into this. i have seen two naturopathic doctors this summer. the one i really liked but the other one's methods landed me in the hospital in august. i tried her program for 3 days and got very sick.
i just started VSL last week. it has helped a lot with my bloating. i've been on 15 mg for a while now and would like to taper but i'm just nervous. the last time i tapered to 10mg i started getting cramps again.
Joanna
Age:21
severe pancolitis
medications: 15 mg prednisone, 50 mg 6mp, and remicade
vitamins and minerals: VSL, 1 multivitamin, calcium, vit D, and zinc citrate.
remicade infusion aug 29, 2011, sept 12, 2011, and next one is oct. 10.
Licorice root
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Bacon Girl
Veteran Member
Date Joined May 2011
Total Posts : 5399
Posted 10/1/2011 12:46 PM (GMT -6)
http://www.herbwisdom.com/herb-licorice-root.html
i found this good website about it. apparently, licorice root helps prevent the breakdown of the adrenal hormones (this happens when we take prednisone) so our natural supply is more available to the body. it also helps heal ulcers, inflammation, and spasms of the digestive tract.
...
Licorice Root (Glycyrrhiza Glabra)
Licorice Root BenefitsMore InfoRelated
Licorice root contains many anti-depressant compounds and is an excellent alternative to St. John's Wort.
As a herbal medicine it has an impressive list of well documented uses and is probably one of the most over-looked of all herbal wonders. Licorice is useful for many ailments including:
Health benefitsHealing substancesHundreds of potentially healing substances have been identified in licorice as well, including compounds called flavonoids and various plant estrogens (phytoestrogens). The herb's key therapeutic compound, glycyrrhizin (which is 50 times sweeter than sugar) exerts numerous beneficial effects on the body, making licorice a valuable herb for treating a host of ailments. It seems to prevent the breakdown of adrenal hormones such as cortisol (the body's primary stress-fighting adrenal hormone), making these hormones more available to the body.
It has a well-documented reputation for healing ulcers. It can lower stomach acid levels, relieve heartburn and indigestion and acts as a mild laxative.
It can also be used for irritation, inflammation and spasm in the digestive tract. Through its beneficial action on the liver, it increases bile flow and lowers cholesterol levels.
Boosts immune system
Licorice also appears to enhance immunity by boosting levels of interferon, a key immune system chemical that fights off attacking viruses. It also contains powerful antioxidants as well as certain phytoestrogens that can perform some of the functions of the body's natural estrogens; very helpful during the menopause. Glycyrrhizinic acid also seems to stop the growth of many bacteria and of viruses such as influenza A.
Relieves pain and stress
It has an aspirin-like action and is helpful in relieving fevers and soothing pain such as headaches. Its anti-allergenic effect is very useful for hay fever, allergic rhinitis, conjunctivitis and bronchial asthma. Possibly by its action on the adrenal glands, licorice has the ability to improve resistance to stress. It should be thought of during times of both physical and emotional stress, after surgery or during convalescence, or when feeling tired and run down.
New research: Licorice hailed for its potential to fight tooth decay
Control respiratory problems and sore throat
Licorice eases congestion and coughing by helping to loosen and thin mucus in airways; this makes a cough more "productive," bringing up phlegm and other mucus bits. Licorice also helps to relax bronchial spasms. The herb also soothes soreness in the throat and fights viruses that cause respiratory illnesses and an overproduction of mucus, such as irritating coughs, asthma and chest infections.
Lessen symptoms of chronic fatigue syndrome and fibromyalgiaBy enhancing cortisol activity, glycyrrhizin helps to increase energy, ease stress and reduce the symptoms of ailments sensitive to cortisol levels, such as chronic fatigue syndrome and fibromylagia.
Combat hepatitis
Licorice both protects the liver and promotes healing in this vital organ. The herb's anti-inflammatory properties help calm hepatitis-associated liver inflammation. Licorice also fights the virus commonly responsible for hepatitis and supplies valuable antioxidant compounds that help maintain the overall health of the liver.
Treat PMS and menstrual problems
The phytoestrogens in licorice have a mild estrogenic effect, making the herb potentially useful in easing certain symptoms of PMS (premenstrual syndrome), such as irritability, bloating and breast tenderness. Although the glycyrrhizin in licorice actually inhibits the effect of the body's own estrogens, the mild estrogenic effect produced by licorice's phytoestrogens manages to override this inhibiting action.
Prevent heart disease
Recent studies have found that by limiting the damage from LDL ("bad") cholesterol, licorice may discourage artery-clogging plaque formation and contribute to the healthy functioning of the heart. Research indicates that modest doses of licorice (100 mg a day) have this effect.
All licorice does is provide an inhibitor to the enzyme that breaks down cortisol so that it circulates longer. I guess that 'supports' adrenals but not how I would phrase it. I have bought bottles of the extract when coming of prednisone. You need to read up on it and time it with your natural cortisol production to extend your natural coritisol because what it really 'support's is your plunging artificial cortisol ( predisone ). I know this space well as I have had adrenal shock from plunging too quickly.
Good luck
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stereofidelic89
Veteran Member
Date Joined Sep 2011
Total Posts : 1964
Posted 10/1/2011 6:54 PM (GMT -6)
Wait are you saying be careful about taking Licorice root??
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seasons21
I'm just letting you know what I"m doing to support my adrenals while on Prednisone. I don't usually take anything without his ok. I really like my ND and I do trust him. He if very knowledgable and he is very particular about the quality of the supplements he suggests. If you are considering taking it, it is good to have someone monitor you.
Back to Top
Peace&Harmony
Have you heard of Flex Now? It' supposed to be "as strong as steroids" but made from Shea nut extract. http://www.powerofshea.com/
My Holistic doctor recommended it. I'm about to start it soon. I'm trying to get of Pred as well. I'm also going to see another Holistic doc regarding Mck. Jefferies protocol. Dr. Mck. Jefferies did extensive research on steroids and was able to switch patents from Pred to Hydrocortisone.
Hydrocortisone is easier to taper off from.
Hydrocortisone is a natural substance (corticosteroid hormone) made by the adrenal gland. It is used to treat conditions such as arthritis, blood/hormone/immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It decreases your immune system's response to various diseases to reduce symptoms such as pain, swelling and allergic-type reactions.
Hydrocortisone is also used to treat low hydrocortisone levels caused by diseases of the adrenal gland (such as Addison's disease, adrenocortical insufficiency). Corticosteroids are needed in many ways for the body to function well.
They are important for salt and water balance and keeping blood pressure normal.
How to use hydrocortisone...
Side Effects
http://www.webmd.com/drugs/2/drug-6731/hydrocortisone-oral/details
Nausea, heartburn, headache, dizziness, menstrual period changes, trouble sleeping, increased sweating, or acne may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Because this drug works by weakening the immune system, it may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as cough, sore throat, fever, chills).
Use of this medication for prolonged or repeated periods may result in oral thrush or a yeast
...
Unfortunately Mck. Jefferies has passed away and a lot of his work is getting lost. He wrote a book on safe uses of cortisols which I read. I have a friend who was treated by his protocol for over 20 years for Crohn's. You can Google Mck. Jefferies. His work is only listed on this doctor's website.
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MustLoveDogs
Regular Member
Date Joined Jan 2009
Total Posts : 394
Posted 10/1/2011 10:11 PM (GMT -6)
There is a homeopathic version of prednisone, but it is extremely difficult to get.
I took my daughter to a naturopath once but she wouldn't prescribe it. Ironically it is used for dogs quite often! Good luck
13 yr old daughter diagnosed UC 12/08
Just spent 8 days in Hospital due to flare & back on Pred :(
Headed for surgery 9/30/11
Remicade: 6/16/11, 7/1/11 and 7/25/11
previously on 6MP, Asacol, Lialda, Rowasa, Cortocoid
Pancreatitis 2/10 after being on Rowasa & Lialda
C-Diff 6/10
Husband dg'd Crohn's 2/09 at age 46 -
Remicade every 8 wks
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greenenergy
New Member
Posted 10/2/2011 8:46 AM (GMT -6)
Slippery Elm is very soothing to the gut. There's also the others mentioned.
I found MSM to be a good anti-inflammatory but it can sometimes cause diarrhea at high doses so need to start at a low dose and build up.
Back to Top
Granwest
New Member
Licorice is one to be very vary of though - if you have high blood pressure as it will cause it to go high even while taking medication. But will be trying some of the above alternatives as have just started taking prednisone for respiratory probs.
Forum Rules | Moderators | Password Help
HealingWell.com Forum > Diseases & Conditions > Ulcerative Colitis > natural alternatives to prednisone??
Select A Location****** Top of the Forum ******==== General Information ====AnnouncementsFrequently Asked QuestionsForum Rules & Guidelines==== Diseases & Conditions ====Allergies & AsthmaAlzheimer's DiseaseAnxiety - Panic DisordersBipolar DisorderBreast CancerCeliac DiseaseChronic Fatigue SyndromeChronic PainCrohn's DiseaseCystic FibrosisDepressionDiabetesEpilepsyFibromyalgiaGERD - HeartburnHeart & Cardiovascular DiseaseHepatitisIrritable Bowel SyndromeKidney Diseases & DisordersLupusLyme DiseaseMigraine - HeadacheMultiple SclerosisOsteoarthritisOstomiesParkinson's DiseaseProstate CancerPsoriasisRheumatoid ArthritisSjogren's SyndromeThyroid DisordersUlcerative Colitis
[ << Previous Thread | Next Thread >> ]
Bacon Girl
i am trying to get off of prednisone and as i taper, i'd like to take something that mimics prednisone's effects without it being a drug. i figure this has to be some kind of anti-inflammatory. any thoughts or suggestions would be great. after most of the spring and summer trying the herbal route, i still have some turmeric and NAG left over.
Joanna
Age:21
severe pancolitis
medications: 15 mg prednisone, 50 mg 6mp, and remicade
vitamins and minerals: VSL, 1 multivitamin, calcium, vit D, and zinc citrate.
remicade infusion aug 29, 2011, sept 12, 2011, and next one is oct. 10.
Back to Top
beachlife
not a replacement for Prednisone in any sense, but ginger and mint both have nice healing/anti-inflammatory effects. Mint Tea from Starbucks REALLY helped me out just this past weekend in Mexico when I had really bad pain, worst I've had in 2 years. But , Prednisone is a steroid, it's strong and does its job, sadly with side affects :-( Been there, done that.
You mentioned herbal route, have you thought about a naturopath dr, or traditional chinese medicine(TCM) Doctor. Contact some of your local holistic centers, they can point you in the right direction. Before I go on Prednisone again I'll probably fly to see a Ayurvedic GI specialist recommended by a friend
good luck, I know prednisone isn't fun, hopefully you at least have good energy!!
Blogging UC:
http://lifewithcolitis.blogspot.com/
Vegan/Pescatarian - ish, , Yoga, Traditional Chinese Medicine
'00 - UC - Proctitis
Lialda 4x/day(2+2)
Testim 1% - Testosterone
Vit D 50,000 ICU/week
VSL#3
Back to Top
bhb5764
Regular Member
Date Joined Nov 2009
Total Posts : 105
Posted 10/1/2011 6:44 AM (GMT -6)
Joanna,
I am in the exact same position as you are. I'm currently weaning off prednisone and I have added in the following supplements in the hope of not re-flaring (I am also continuing on Humira, Asacol, and Rowasa, VSL#3): tumeric, slippery elm, boswellia, and ginger, all of which are supposed to have anti-inflammatory properties. For guidance on dosage, I looked at the University of Maryland's site on alternative medicines for UC: http://www.umm.edu/altmed/articles/ulcerative-colitis-002684.htm. Also, there are many people on this forum that have had good results from tumeric and boswellia, so you can get some more info by searching those herbs.
I did actually go to see a doctor who is an MD but practices only homeopathic medicine (It was VERY expensive b/c she doesn't accept insurance, but I am pretty desperate to get off prednisone and prevent the next flare). I wasn't too happy with the overall experience because I felt that she was not taking into account the autoimmune and inflammatory nature of UC and was basically recommending supplements that would be better suited for someone with IBS (however, I could totally be wrong. I just was surprised that nothing she recommended had any of the herbs listed above in them). In any case, here are the supplements she recommended--I haven't taken them yet but will try them if I start to flare again on the taper: GlutAloeMine (brand name), Gastrex (brand name made by Standard Process), Gut Flora Complex (made by MediHerb), and Zypan (brand name made by Standard Process).
Hope you get off prednisone soon!
Bridget
11 years of UC
Currently taking: Asacol, Rowasa, Canasa, Humira (started 4/11), tumeric, ginger, boswellia, slippery elm, VSL#3
Discontinued: Remicade
Back to Top
seasons21
Veteran Member
Date Joined Aug 2004
Total Posts : 633
Posted 10/1/2011 8:38 AM (GMT -6)
I am tapering also. The whole time I've been on Prednisone my naturopath has me taking liquid licorice root. He was adamant that I take it. He said it would support my adrenals. I was doing 1/4 tsp once in am and once around noon. He wants me to increase it my 1/4 tsp as I taper. It is also anti inflammatory and he said it would keep the Prednisone in me longer so I would need less.
I pray we both get off. BTW are you still having any sxs? I am not completely sx free and I am not on maintenace meds. Too scared to do immunos yet. We'll see. I pray I'm not at square one again.
Back to Top
suebear
Forum Moderator
Date Joined Feb 2006
Total Posts : 5621
Posted 10/1/2011 9:31 AM (GMT -6)
Just remember that natural does not mean safe or healthier than Rxs. Most of our Rx drugs evolved from plants. Differences are in rigorous testing. I'm not opposed to herbal and alternative treatments, did them myself, but don't be fooled into thinking they are safer.
Sue
Back to Top
journey2health
Veteran Member
Date Joined Oct 2009
Total Posts : 2787
Posted 10/1/2011 9:49 AM (GMT -6)
Are you taking a probiotic? Turmeric is also recommended as an anti-inflammatory though it did nothing for me.
In remission (yippee!)--pancolitis since 8/09. Asacol 3200 mg. Canasa or Rowasa daily, Probiotic -RenewLife Ultimate Flora Critical Care, vitamins, calcium, l-acetyl carnitine. Limit dairy, red meat, citrus, sugar, no alcohol. Bipolar/anxiety/depression: lamictal 200 mg, Lexapro 10 mg; wellbutrin 150 mg, Sleep-(ZMA) zinc-magnesium-B6, occasional Zyprexa 2.5 mg.
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beachlife
Regular Member
Date Joined Feb 2009
Total Posts : 473
Posted 10/1/2011 10:52 AM (GMT -6)
interesting on the licorice root. One of the herbs in my herbal tea is "radix glycyrrhizae (Liquorice)"
Blogging UC:
http://lifewithcolitis.blogspot.com/
Vegan/Pescatarian - ish, , Yoga, Traditional Chinese Medicine
'00 - UC - Proctitis
Lialda 4x/day(2+2)
Testim 1% - Testosterone
Vit D 50,000 ICU/week
VSL#3
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Bacon Girl
Veteran Member
Date Joined May 2011
Total Posts : 5399
Posted 10/1/2011 12:39 PM (GMT -6)
yeah, i haven't heard about licorice root either. i will look into this. i have seen two naturopathic doctors this summer. the one i really liked but the other one's methods landed me in the hospital in august. i tried her program for 3 days and got very sick.
i just started VSL last week. it has helped a lot with my bloating. i've been on 15 mg for a while now and would like to taper but i'm just nervous. the last time i tapered to 10mg i started getting cramps again.
Joanna
Age:21
severe pancolitis
medications: 15 mg prednisone, 50 mg 6mp, and remicade
vitamins and minerals: VSL, 1 multivitamin, calcium, vit D, and zinc citrate.
remicade infusion aug 29, 2011, sept 12, 2011, and next one is oct. 10.
Licorice root
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Bacon Girl
Veteran Member
Date Joined May 2011
Total Posts : 5399
Posted 10/1/2011 12:46 PM (GMT -6)
http://www.herbwisdom.com/herb-licorice-root.html
i found this good website about it. apparently, licorice root helps prevent the breakdown of the adrenal hormones (this happens when we take prednisone) so our natural supply is more available to the body. it also helps heal ulcers, inflammation, and spasms of the digestive tract.
...
Licorice Root (Glycyrrhiza Glabra)
Licorice Root BenefitsMore InfoRelated
Licorice root contains many anti-depressant compounds and is an excellent alternative to St. John's Wort.
As a herbal medicine it has an impressive list of well documented uses and is probably one of the most over-looked of all herbal wonders. Licorice is useful for many ailments including:
Health benefitsHealing substancesHundreds of potentially healing substances have been identified in licorice as well, including compounds called flavonoids and various plant estrogens (phytoestrogens). The herb's key therapeutic compound, glycyrrhizin (which is 50 times sweeter than sugar) exerts numerous beneficial effects on the body, making licorice a valuable herb for treating a host of ailments. It seems to prevent the breakdown of adrenal hormones such as cortisol (the body's primary stress-fighting adrenal hormone), making these hormones more available to the body.
It has a well-documented reputation for healing ulcers. It can lower stomach acid levels, relieve heartburn and indigestion and acts as a mild laxative.
It can also be used for irritation, inflammation and spasm in the digestive tract. Through its beneficial action on the liver, it increases bile flow and lowers cholesterol levels.
Boosts immune system
Licorice also appears to enhance immunity by boosting levels of interferon, a key immune system chemical that fights off attacking viruses. It also contains powerful antioxidants as well as certain phytoestrogens that can perform some of the functions of the body's natural estrogens; very helpful during the menopause. Glycyrrhizinic acid also seems to stop the growth of many bacteria and of viruses such as influenza A.
Relieves pain and stress
It has an aspirin-like action and is helpful in relieving fevers and soothing pain such as headaches. Its anti-allergenic effect is very useful for hay fever, allergic rhinitis, conjunctivitis and bronchial asthma. Possibly by its action on the adrenal glands, licorice has the ability to improve resistance to stress. It should be thought of during times of both physical and emotional stress, after surgery or during convalescence, or when feeling tired and run down.
New research: Licorice hailed for its potential to fight tooth decay
Control respiratory problems and sore throat
Licorice eases congestion and coughing by helping to loosen and thin mucus in airways; this makes a cough more "productive," bringing up phlegm and other mucus bits. Licorice also helps to relax bronchial spasms. The herb also soothes soreness in the throat and fights viruses that cause respiratory illnesses and an overproduction of mucus, such as irritating coughs, asthma and chest infections.
Lessen symptoms of chronic fatigue syndrome and fibromyalgiaBy enhancing cortisol activity, glycyrrhizin helps to increase energy, ease stress and reduce the symptoms of ailments sensitive to cortisol levels, such as chronic fatigue syndrome and fibromylagia.
Combat hepatitis
Licorice both protects the liver and promotes healing in this vital organ. The herb's anti-inflammatory properties help calm hepatitis-associated liver inflammation. Licorice also fights the virus commonly responsible for hepatitis and supplies valuable antioxidant compounds that help maintain the overall health of the liver.
Treat PMS and menstrual problems
The phytoestrogens in licorice have a mild estrogenic effect, making the herb potentially useful in easing certain symptoms of PMS (premenstrual syndrome), such as irritability, bloating and breast tenderness. Although the glycyrrhizin in licorice actually inhibits the effect of the body's own estrogens, the mild estrogenic effect produced by licorice's phytoestrogens manages to override this inhibiting action.
Prevent heart disease
Recent studies have found that by limiting the damage from LDL ("bad") cholesterol, licorice may discourage artery-clogging plaque formation and contribute to the healthy functioning of the heart. Research indicates that modest doses of licorice (100 mg a day) have this effect.
All licorice does is provide an inhibitor to the enzyme that breaks down cortisol so that it circulates longer. I guess that 'supports' adrenals but not how I would phrase it. I have bought bottles of the extract when coming of prednisone. You need to read up on it and time it with your natural cortisol production to extend your natural coritisol because what it really 'support's is your plunging artificial cortisol ( predisone ). I know this space well as I have had adrenal shock from plunging too quickly.
Good luck
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stereofidelic89
Veteran Member
Date Joined Sep 2011
Total Posts : 1964
Posted 10/1/2011 6:54 PM (GMT -6)
Wait are you saying be careful about taking Licorice root??
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seasons21
I'm just letting you know what I"m doing to support my adrenals while on Prednisone. I don't usually take anything without his ok. I really like my ND and I do trust him. He if very knowledgable and he is very particular about the quality of the supplements he suggests. If you are considering taking it, it is good to have someone monitor you.
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Peace&Harmony
Have you heard of Flex Now? It' supposed to be "as strong as steroids" but made from Shea nut extract. http://www.powerofshea.com/
My Holistic doctor recommended it. I'm about to start it soon. I'm trying to get of Pred as well. I'm also going to see another Holistic doc regarding Mck. Jefferies protocol. Dr. Mck. Jefferies did extensive research on steroids and was able to switch patents from Pred to Hydrocortisone.
Hydrocortisone is easier to taper off from.
Hydrocortisone is a natural substance (corticosteroid hormone) made by the adrenal gland. It is used to treat conditions such as arthritis, blood/hormone/immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It decreases your immune system's response to various diseases to reduce symptoms such as pain, swelling and allergic-type reactions.
Hydrocortisone is also used to treat low hydrocortisone levels caused by diseases of the adrenal gland (such as Addison's disease, adrenocortical insufficiency). Corticosteroids are needed in many ways for the body to function well.
They are important for salt and water balance and keeping blood pressure normal.
How to use hydrocortisone...
Side Effects
http://www.webmd.com/drugs/2/drug-6731/hydrocortisone-oral/details
Nausea, heartburn, headache, dizziness, menstrual period changes, trouble sleeping, increased sweating, or acne may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Because this drug works by weakening the immune system, it may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as cough, sore throat, fever, chills).
Use of this medication for prolonged or repeated periods may result in oral thrush or a yeast
...
Unfortunately Mck. Jefferies has passed away and a lot of his work is getting lost. He wrote a book on safe uses of cortisols which I read. I have a friend who was treated by his protocol for over 20 years for Crohn's. You can Google Mck. Jefferies. His work is only listed on this doctor's website.
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MustLoveDogs
Regular Member
Date Joined Jan 2009
Total Posts : 394
Posted 10/1/2011 10:11 PM (GMT -6)
There is a homeopathic version of prednisone, but it is extremely difficult to get.
I took my daughter to a naturopath once but she wouldn't prescribe it. Ironically it is used for dogs quite often! Good luck
13 yr old daughter diagnosed UC 12/08
Just spent 8 days in Hospital due to flare & back on Pred :(
Headed for surgery 9/30/11
Remicade: 6/16/11, 7/1/11 and 7/25/11
previously on 6MP, Asacol, Lialda, Rowasa, Cortocoid
Pancreatitis 2/10 after being on Rowasa & Lialda
C-Diff 6/10
Husband dg'd Crohn's 2/09 at age 46 -
Remicade every 8 wks
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greenenergy
New Member
Posted 10/2/2011 8:46 AM (GMT -6)
Slippery Elm is very soothing to the gut. There's also the others mentioned.
I found MSM to be a good anti-inflammatory but it can sometimes cause diarrhea at high doses so need to start at a low dose and build up.
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Granwest
New Member
Licorice is one to be very vary of though - if you have high blood pressure as it will cause it to go high even while taking medication. But will be trying some of the above alternatives as have just started taking prednisone for respiratory probs.
MEDROL
http://forums.spondylitis.org/ubbthreads.php?ubb=showflat&Number=235162
Re: Long-term oral Medrol (Methylprednisolone) for AS?
The problem with long-term steroid use is that it can mess with your adrenal glands. This means that after a while, if you stop, you risk your adrenals not being able to produce steroid hormones again. I know there is someone else on here who was on long-term steroids, and she is suffering from adrenal insufficiency because of it. There are also tons of other concerns. It is great that you are in good shape, but that does not necessarily mean that you are immune to the potential side effects of long-term usage.
As for me, I was on and off Prednisone (mostly on) for about 5 or 6 months. At one point I was on a very high dose. Even on the lower dosages, I definitely felt significant improvement, but after a while of being on it for so long, I was beginning to feel the adverse effects of it. I have weaned off now, and some days it is so tempting to call my rheumy and plead to go back on. However, I am very nervous when it comes to steroids.
_________________________
Kim - age 33
DX: Psoriatic Arthritis, HLA B27+
Meds: Otezla, Naproxen PRN, Prednisone PRN
On Sun, May 22, 2016 at 1:31 PM, <[email protected]> wrote:
Yes…been on and off it off it for years. Began 16mg/day of oral Medrol in Sept ’16 due to my first flare up of AS-related Uveitis/Scleritis and have been on it since.
Began to taper off of it about a month ago and am now down to 12mg/day.
Medrol is a fantastic med for me. It is not supposed to work for AS but it does in me. Also, I have none of the typical steroid side-effects (weight gain, sleeplessness, sweating, depression/anxiety, etc.) and am monitored for the longer term side effects (glaucoma, osteoporosis, elevated glucose levels, etc.).
[email protected]1:57 PM
I am certainly not a doctor and any decision like this should be made only after careful consideration of the risks/rewards of going on any corticosteroid long-term, especially if you have already developed substantial and irreversible side-effects (which it sounds like you have). That said, trying to maintain some semblance of quality of life is also important when you have a chronic disease.
BTW….did you ever get off the prednisone or did the doc just transition you to Medrol? In other words, are you now permanently physically dependent on the steroids? If you are already physically dependent on the steroids, then giving the Medrol a shot sounds like an easier decision to make. If you got off the steroids and are now looking at going back on them, that is a tougher decision, especially if you have osteoporosis.
Sounds like you have to decide if the risk is worth the reward to your quality of life now AND in the future. Very tough decision and a decision only you can make.
Hope this helps…wishing you all the best.
Methylpednisolons >> Prednisone
Methylprednisolone is a more "potent" type of corticosteroid. It is very similar to Prednisone, and they are often used interchangeably, but it is not the same thing. Which is "better" is dependent on its use. It may even be a matter of doctor's preference.
Corticosteroids all work about the same in the body. The biggest difference is how closely they resemble the "natural" form of cortisol. Dosage is adjusted to attain desired results, and they are ALL interchangeable. The exceptions to interchangeable would be if you are taking other medication with the steroid. Some antibiotics and blood thinners, for example, work differently with prednisone on board. You can adjust the dosage of Prednisone, or methylprednisolone, to the equivilent of hydrocortisone (more similar to the natural cortisol), or the other cortisol synthetics.
4 mg methylpred = 5 mg prednisone = 20 mg hydrocortisone.
One other thing to factor in... There are three classes of these. The short-acting, intermediate acting and long acting. Pred and Methylpred are intermediate acting. Hydrocortisone, is a short acting, and usually requires a twice or more daily dose. Dexamethasone is a long acting and is given in smaller doses and possibly even every other day. All Corticosteroid "rules" apply to any one of them. Don't stop taking it suddenly. Don't use for longer than the doctor orders without re-evaluation, etc. If you have taken it before, you are familiar with the rules and the reasons. Hope this helps.
http://forums.spondylitis.org/ubbthreads.php?ubb=showflat&Number=235162
Re: Long-term oral Medrol (Methylprednisolone) for AS?
The problem with long-term steroid use is that it can mess with your adrenal glands. This means that after a while, if you stop, you risk your adrenals not being able to produce steroid hormones again. I know there is someone else on here who was on long-term steroids, and she is suffering from adrenal insufficiency because of it. There are also tons of other concerns. It is great that you are in good shape, but that does not necessarily mean that you are immune to the potential side effects of long-term usage.
As for me, I was on and off Prednisone (mostly on) for about 5 or 6 months. At one point I was on a very high dose. Even on the lower dosages, I definitely felt significant improvement, but after a while of being on it for so long, I was beginning to feel the adverse effects of it. I have weaned off now, and some days it is so tempting to call my rheumy and plead to go back on. However, I am very nervous when it comes to steroids.
_________________________
Kim - age 33
DX: Psoriatic Arthritis, HLA B27+
Meds: Otezla, Naproxen PRN, Prednisone PRN
On Sun, May 22, 2016 at 1:31 PM, <[email protected]> wrote:
Yes…been on and off it off it for years. Began 16mg/day of oral Medrol in Sept ’16 due to my first flare up of AS-related Uveitis/Scleritis and have been on it since.
Began to taper off of it about a month ago and am now down to 12mg/day.
Medrol is a fantastic med for me. It is not supposed to work for AS but it does in me. Also, I have none of the typical steroid side-effects (weight gain, sleeplessness, sweating, depression/anxiety, etc.) and am monitored for the longer term side effects (glaucoma, osteoporosis, elevated glucose levels, etc.).
[email protected]1:57 PM
I am certainly not a doctor and any decision like this should be made only after careful consideration of the risks/rewards of going on any corticosteroid long-term, especially if you have already developed substantial and irreversible side-effects (which it sounds like you have). That said, trying to maintain some semblance of quality of life is also important when you have a chronic disease.
BTW….did you ever get off the prednisone or did the doc just transition you to Medrol? In other words, are you now permanently physically dependent on the steroids? If you are already physically dependent on the steroids, then giving the Medrol a shot sounds like an easier decision to make. If you got off the steroids and are now looking at going back on them, that is a tougher decision, especially if you have osteoporosis.
Sounds like you have to decide if the risk is worth the reward to your quality of life now AND in the future. Very tough decision and a decision only you can make.
Hope this helps…wishing you all the best.
Methylpednisolons >> Prednisone
Methylprednisolone is a more "potent" type of corticosteroid. It is very similar to Prednisone, and they are often used interchangeably, but it is not the same thing. Which is "better" is dependent on its use. It may even be a matter of doctor's preference.
Corticosteroids all work about the same in the body. The biggest difference is how closely they resemble the "natural" form of cortisol. Dosage is adjusted to attain desired results, and they are ALL interchangeable. The exceptions to interchangeable would be if you are taking other medication with the steroid. Some antibiotics and blood thinners, for example, work differently with prednisone on board. You can adjust the dosage of Prednisone, or methylprednisolone, to the equivilent of hydrocortisone (more similar to the natural cortisol), or the other cortisol synthetics.
4 mg methylpred = 5 mg prednisone = 20 mg hydrocortisone.
One other thing to factor in... There are three classes of these. The short-acting, intermediate acting and long acting. Pred and Methylpred are intermediate acting. Hydrocortisone, is a short acting, and usually requires a twice or more daily dose. Dexamethasone is a long acting and is given in smaller doses and possibly even every other day. All Corticosteroid "rules" apply to any one of them. Don't stop taking it suddenly. Don't use for longer than the doctor orders without re-evaluation, etc. If you have taken it before, you are familiar with the rules and the reasons. Hope this helps.
Medrol
Select Language▼Generic Name: Methylprednisolone
Other Trade Names: Duralone®, Medralone®, M-Prednisol®, Solu-Medrol®
Other Names: 6-Methylprednisolone, Methylprednisolone Acetate, Methylprednisolone Sodium Succinate
Drug Type:
Medrol has many uses in the treatment of cancer. Medrol is most often as a supportive care medication. Medrol is classified as a glucocorticosteroid. (For more detail, see "How Medrol Works" section below).
What Is Medrol Used For:
How Medrol Is Given:
Medrol Side Effects:
Important things to remember about Medrol side effects:
When To Contact Your Doctor or Health Care Provider:
Contact your health care provider immediately, day or night, if you should experience any of the following symptoms:
Medrol Precautions:
Medrol Self Care Tips:
You will be checked regularly by your health care professional while you are taking Medrol, to monitor side effects and check your response to therapy. Periodic blood work to monitor your complete blood count (CBC) as well as the function of other organs (such as your kidneys and liver) will also be ordered by your doctor.
How Medrol Works:
Corticosteroids are naturally produced by the adrenal gland in the body. Corticosteroids influence the functioning of most of the body's systems (heart, immune, muscles and bones, endocrine and nervous system). They exert a wide array of effects including effects on the metabolism of carbohydrates, protein and fats. They help to maintain balance of fluids and electrolytes.
Medrol is classified as a corticosteroid (more precisely a glucocorticosteroid), and has many uses in the treatment of cancer.
One way that it works is to decrease inflammation (swelling). It does this by preventing infection- fighting white blood cells (polymorphonuclear leukocytes) from traveling to the area of swelling in your body. (This is why you are more prone to infection while taking steroids). Taking advantage of the anti-inflammatory properties of the medication, corticosteroids are used to decrease the swelling around tumors. For example, by decreasing swelling around tumors in the spine, brain, or bone, it can decrease the pressure of the tumor on nerve endings and relieve pain or other symptoms caused by the pressing tumor.
Another way Medrol works is by altering the body's normal immune system responses. Corticosteroids are used to treat certain conditions that effect the immune system such as aplastic anemia (AA), Immune Thrombocytopenia Purpura (ITP), Thrombotic Thrombocytopenia Purpura (TTP), or hemolytic anemia.
In addition, it is thought that corticosteroids may help in the treatment of patients with blood disorders, such as multiple myeloma. Corticosteroids may work by causing programmed cell death (apoptosis) of certain cells, which may help to fight your disease.
Corticosteroids are also used in the short-term treatment of nausea caused by chemotherapy. How it does this is not fully understood. They also have been used to stimulate appetite for patients with severe appetite problems.
Corticosteroids are used to replace steroids in conditions of adrenal insufficiency (low production of needed steroids produced by the adrenal glands).
Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice.
http://chemocare.com/chemotherapy/drug-info/Medrol.aspx
Question:
Medrol and methotrexate long term?
dbacs - Tue Jan 31, 2006 10:14 am Share|
I have been trying to get off of medrol and on to methotrexate only. I cannot get below 4mg of medrol or my ears and chronic hives flare up. I have been doing this for almost a year now and i cannot get off of medrol.
I have started methotrexate last month and it seems to help a little bit.
So as it seems i don't think I'll ever be able to get off the medrol.
Is 4 mg and methotrexate, 10mg, safe for long term use?
I am disabled when i am not on the medrol. I want to get on with my life. Can i TELL my doctor to keep me on the medrol?
I am 31 and 135 pounds in excellent health otherwise.
R. Zein, Pharm D - Tue Jan 31, 2006 12:21 pm Share|
Dear dbacs
Medrol belongs to group of medicines known as Glucocorticoids , which are are naturally occurring hormones that prevent or suppress inflammation and immune responses when administered at pharmacological doses
The severity of the adverse effects associated with prolonged administration of pharmacological dosages of corticosteroids increases with duration and frequency of therapy. Short-term administration of large doses typically does not cause adverse effects, but long-term administration can lead to adrenocortical atrophy and generalized protein depletion.
In your case, the dose you are taking is considered low. high doses per see are when we talk about dosing of i mg/kg, which is not the case in yours.
However, i may stress on the importance of patient education regarding possible symptoms which have been associated with chronic use and usually with high doses:
Glucocorticoids are responsible for protein metabolism, and prolonged therapy can result in various musculoskeletal manifestations, including: myopathy (myalgia, muscle wasting, muscle weakness), impaired wound healing, bone matrix atrophy (osteoporosis), and bone fractures. These effects are more likely to occur in older or debilitated patients.
Glucocorticoids interact with calcium metabolism at many sites, including: decreasing the synthesis by osteoblasts of the principle proteins of bone matrix, malabsorption of calcium in both the nephron and the gut, and reduction of sex hormone concentrations. Although all of these actions probably contribute to glucocorticoid-induced osteoporosis, the actions on osteoblasts is most important. Glucocorticoids do not modify vitamin D metabolism. Postmenopausal women, in particular, should be monitored for signs of osteoporosis during corticosteroid therapy.
Again , these symptoms occur mainly in elderly, not in young patients.
In addition, Corticosteroid therapy can mask the symptoms of infection and should be avoided during an acute viral or bacterial infection. Immunosuppression is most likely to occur in patients receiving high-dose (e.g., equivalent to 1 mg/kg or more of prednisone daily).
Also, various adverse dermatologic effects reported during corticosteroid therapy include skin atrophy, acne vulgaris, diaphoresis, impaired wound healing, facial erythema, striae, petechiae, hirsutism, ecchymosis, and easy bruising. Hypersensitivity reactions may manifest as allergic dermatitis, urticaria, and/or angioedema.
And very importantly, pharmacologic doses of corticosteroids administered for prolonged periods can result in physiological dependence due to hypothalamic-pituitary-adrenal (HPA) suppression. This inhibition decreases ACTH-mediated synthesis of endogenous corticosteroids and androgens by the adrenal cortex. The severity of glucocorticoid-induced secondary adrenocortical insufficiency varies among individuals and is dependent on the dose, frequency, time of administration, and duration of therapy. Administering the drug on alternate days may help to alleviate this adverse effect. Patients with HPA suppression will require increased doses of corticosteroids during periods of physiologic stress.
I am mentioning this to you, in case you decide to quit it one day, make sure to do it gradual, this is because HPA suppression can last for up to 12 months following cessation of therapy.
Other possible side effects can include hypercholesterolemia, atherosclerosis, fat embolism, hyperglycemia, increase in blood pressure due to fluid retention. Corticosteroids may also decrease serum concentrations of vitamin C (ascorbic acid) and vitamin A which may rarely produce symptoms of vitamin A deficiency or vitamin C deficiency
While on long term use of medrol, you should monitor the followings, blood glucose, PFTs, and serum potassium
Select Language▼Generic Name: Methylprednisolone
Other Trade Names: Duralone®, Medralone®, M-Prednisol®, Solu-Medrol®
Other Names: 6-Methylprednisolone, Methylprednisolone Acetate, Methylprednisolone Sodium Succinate
Drug Type:
Medrol has many uses in the treatment of cancer. Medrol is most often as a supportive care medication. Medrol is classified as a glucocorticosteroid. (For more detail, see "How Medrol Works" section below).
What Is Medrol Used For:
- As an anti-inflammatory medication. Prednisolone relieves inflammation in various parts of the body.
- To treat or prevent allergic reactions.
- As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions.
- As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma.
- To treat nausea and vomiting associated with some chemotherapy drugs.
- Used to stimulate appetite in cancer patients with severe appetite problems.
- Also used to replace steroids in conditions of adrenal insufficiency (low production of needed steroids produced by the adrenal glands).
- Used as prevention and treatment of graft-versus-host disease following allogeneic bone marrow transplantation.
How Medrol Is Given:
- Medrol may be given to you in many forms. In a pill form, it is available in 2 mg, 4 mg, 8mg, 16mg, 24mg and 32 mg tablets. If you are on a daily dose of Medrol, and you miss a dose, take the dose as soon as you remember.
- Take Medrol pills with food or after meals.
- Medrol may also be given by injection into the muscle (intramuscular, IM) or into the vein (intravenously, IV), by a healthcare provider.
- The amount of hydrocortisone you will receive depends on many factors, including your height and weight, your general health or other health problems, and the reason you are receiving Medrol. Your doctor will determine your exact dosage and schedule.
Medrol Side Effects:
Important things to remember about Medrol side effects:
- Most people do not experience all of the Medrol side effects listed.
- Medrol side effects are often predictable in terms of their onset and duration.
- Medrol side effects are almost always reversible and will go away after treatment is complete.
- There are many options to help minimize or prevent Medrol side effects.
- Increased appetite
- Irritability
- Difficulty sleeping (insomnia)
- Swelling in your ankles and feet (fluid retention)
- Nausea, take with food
- Heartburn
- Muscle weakness
- Impaired wound healing
- Increased blood sugar levels. Persons with Diabetes may need to have blood sugar levels monitored more closely and possible adjustments to diabetes medications.
- Headaches
- Dizziness
- Mood swings
- Cataracts and bone thinning (with long-term use)
When To Contact Your Doctor or Health Care Provider:
Contact your health care provider immediately, day or night, if you should experience any of the following symptoms:
- Fever of 100.4° F (38° C), chills (possible signs of infection)
- If you feel an irregular or fast heart beat, shortness of breath, or chest or jaw pain, seek emergency help and notify your healthcare provider.
- If you become suddenly confused.
- Extreme fatigue (unable to carry on self-care activities)
- Any unusual bleeding or bruising
- Black or tarry stools, or blood in your stools or urine
- Nausea (interferes with ability to eat and unrelieved with prescribed medications)
- Vomiting (vomiting more than 4-5 times in a 24-hour period)
- Dizziness or lightheadedness, feeling faint.
- Persistent headache
- Severe hot flashes or mood swings
- Inability to sleep (insomnia)
- Severe skeletal (bone) pain
- Difficult or painful urination; increased urination, or severe thirst
- Changes in vision, blurred vision, eye pain, enlarged pupils, discharge
- Any new rashes or changes in your skin
- Swelling of the feet or ankles. Sudden weight gain (greater than 3 pounds a week)
- Swelling, redness and/or pain in one leg or arm and not the other
Medrol Precautions:
- Before starting Medrol treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
- Do not receive any kind of immunization or vaccination without your doctor's approval while taking Medrol.
- If you have been on Medrol pills daily, for a long period of time, serious side effects may occur if you discontinue the medication abruptly. Do not stop taking Medrol unless directed by your healthcare provider. Do not change the dose of Medrol on your own.
- Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category C (use in pregnancy only when benefit to the mother outweighs risk to the fetus).
- For both men and women: Do not conceive a child (get pregnant) while taking Medrol. Barrier methods of contraception, such as condoms, are recommended. Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.
- Do not breast feed while taking Medrol.
Medrol Self Care Tips:
- If you are on Medrol for a long period of time, you may be more susceptible to infection. Wash your hands well, and report any symptoms of infection to your healthcare provider if noted.
- In a pill form: Take Medrol with food to lessen an upset stomach. Also take Medrol early on in the day (before 12:00 noon, if possible), so you will be able to sleep better at night.
- If you have diabetes, Medrol may increase your blood sugar levels. Notify your healthcare provider that you are diabetic. You may need close monitoring.
- Drink 2 to 3 quarts of fluid every 24 hours, unless you were told to restrict your fluid intake, and maintain good nutrition.
- To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
- In general, drinking alcoholic beverages should be avoided. You should also limit caffeine intake (colas, tea, coffee and chocolate, especially). These beverages may irritate your stomach.
- If you experience symptoms or side effects, especially if severe, be sure to discuss them with your health care team. They can prescribe medications and/or offer other suggestions that are effective in managing such problems.
You will be checked regularly by your health care professional while you are taking Medrol, to monitor side effects and check your response to therapy. Periodic blood work to monitor your complete blood count (CBC) as well as the function of other organs (such as your kidneys and liver) will also be ordered by your doctor.
How Medrol Works:
Corticosteroids are naturally produced by the adrenal gland in the body. Corticosteroids influence the functioning of most of the body's systems (heart, immune, muscles and bones, endocrine and nervous system). They exert a wide array of effects including effects on the metabolism of carbohydrates, protein and fats. They help to maintain balance of fluids and electrolytes.
Medrol is classified as a corticosteroid (more precisely a glucocorticosteroid), and has many uses in the treatment of cancer.
One way that it works is to decrease inflammation (swelling). It does this by preventing infection- fighting white blood cells (polymorphonuclear leukocytes) from traveling to the area of swelling in your body. (This is why you are more prone to infection while taking steroids). Taking advantage of the anti-inflammatory properties of the medication, corticosteroids are used to decrease the swelling around tumors. For example, by decreasing swelling around tumors in the spine, brain, or bone, it can decrease the pressure of the tumor on nerve endings and relieve pain or other symptoms caused by the pressing tumor.
Another way Medrol works is by altering the body's normal immune system responses. Corticosteroids are used to treat certain conditions that effect the immune system such as aplastic anemia (AA), Immune Thrombocytopenia Purpura (ITP), Thrombotic Thrombocytopenia Purpura (TTP), or hemolytic anemia.
In addition, it is thought that corticosteroids may help in the treatment of patients with blood disorders, such as multiple myeloma. Corticosteroids may work by causing programmed cell death (apoptosis) of certain cells, which may help to fight your disease.
Corticosteroids are also used in the short-term treatment of nausea caused by chemotherapy. How it does this is not fully understood. They also have been used to stimulate appetite for patients with severe appetite problems.
Corticosteroids are used to replace steroids in conditions of adrenal insufficiency (low production of needed steroids produced by the adrenal glands).
Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice.
http://chemocare.com/chemotherapy/drug-info/Medrol.aspx
Question:
Medrol and methotrexate long term?
dbacs - Tue Jan 31, 2006 10:14 am Share|
I have been trying to get off of medrol and on to methotrexate only. I cannot get below 4mg of medrol or my ears and chronic hives flare up. I have been doing this for almost a year now and i cannot get off of medrol.
I have started methotrexate last month and it seems to help a little bit.
So as it seems i don't think I'll ever be able to get off the medrol.
Is 4 mg and methotrexate, 10mg, safe for long term use?
I am disabled when i am not on the medrol. I want to get on with my life. Can i TELL my doctor to keep me on the medrol?
I am 31 and 135 pounds in excellent health otherwise.
R. Zein, Pharm D - Tue Jan 31, 2006 12:21 pm Share|
Dear dbacs
Medrol belongs to group of medicines known as Glucocorticoids , which are are naturally occurring hormones that prevent or suppress inflammation and immune responses when administered at pharmacological doses
The severity of the adverse effects associated with prolonged administration of pharmacological dosages of corticosteroids increases with duration and frequency of therapy. Short-term administration of large doses typically does not cause adverse effects, but long-term administration can lead to adrenocortical atrophy and generalized protein depletion.
In your case, the dose you are taking is considered low. high doses per see are when we talk about dosing of i mg/kg, which is not the case in yours.
However, i may stress on the importance of patient education regarding possible symptoms which have been associated with chronic use and usually with high doses:
Glucocorticoids are responsible for protein metabolism, and prolonged therapy can result in various musculoskeletal manifestations, including: myopathy (myalgia, muscle wasting, muscle weakness), impaired wound healing, bone matrix atrophy (osteoporosis), and bone fractures. These effects are more likely to occur in older or debilitated patients.
Glucocorticoids interact with calcium metabolism at many sites, including: decreasing the synthesis by osteoblasts of the principle proteins of bone matrix, malabsorption of calcium in both the nephron and the gut, and reduction of sex hormone concentrations. Although all of these actions probably contribute to glucocorticoid-induced osteoporosis, the actions on osteoblasts is most important. Glucocorticoids do not modify vitamin D metabolism. Postmenopausal women, in particular, should be monitored for signs of osteoporosis during corticosteroid therapy.
Again , these symptoms occur mainly in elderly, not in young patients.
In addition, Corticosteroid therapy can mask the symptoms of infection and should be avoided during an acute viral or bacterial infection. Immunosuppression is most likely to occur in patients receiving high-dose (e.g., equivalent to 1 mg/kg or more of prednisone daily).
Also, various adverse dermatologic effects reported during corticosteroid therapy include skin atrophy, acne vulgaris, diaphoresis, impaired wound healing, facial erythema, striae, petechiae, hirsutism, ecchymosis, and easy bruising. Hypersensitivity reactions may manifest as allergic dermatitis, urticaria, and/or angioedema.
And very importantly, pharmacologic doses of corticosteroids administered for prolonged periods can result in physiological dependence due to hypothalamic-pituitary-adrenal (HPA) suppression. This inhibition decreases ACTH-mediated synthesis of endogenous corticosteroids and androgens by the adrenal cortex. The severity of glucocorticoid-induced secondary adrenocortical insufficiency varies among individuals and is dependent on the dose, frequency, time of administration, and duration of therapy. Administering the drug on alternate days may help to alleviate this adverse effect. Patients with HPA suppression will require increased doses of corticosteroids during periods of physiologic stress.
I am mentioning this to you, in case you decide to quit it one day, make sure to do it gradual, this is because HPA suppression can last for up to 12 months following cessation of therapy.
Other possible side effects can include hypercholesterolemia, atherosclerosis, fat embolism, hyperglycemia, increase in blood pressure due to fluid retention. Corticosteroids may also decrease serum concentrations of vitamin C (ascorbic acid) and vitamin A which may rarely produce symptoms of vitamin A deficiency or vitamin C deficiency
While on long term use of medrol, you should monitor the followings, blood glucose, PFTs, and serum potassium
Send to
J Allergy Clin Immunol. 1989 Dec;84(6 Pt 1):867-73.
Penetration of corticosteroids into the lung: evidence for a
difference between methylprednisolone and prednisolone.
Vichyanond P1, Irvin CG, Larsen GL, Szefler SJ, Hill MR.Author information
Abstract
Little is known about the penetration of corticosteroids, such as methylprednisolone and prednisolone, into the lung, despite their common use in the treatment of inflammatory lung diseases. To compare methylprednisolone and prednisolone concentrations in the bronchoalveolar space, we administered these two corticosteroids in a randomized, crossover fashion to 17 adult rabbits.
A loading dose was administered and was followed by a continuous infusion for 180 minutes to achieve steady-state plasma concentrations between 200 to 2000 ng/ml. Serial plasma samples were obtained during the infusions. Bronchoalveolar lavages (BAL) were performed at 180 minutes with sterile saline. Plasma and BAL fluid (BALF) were assayed for methylprednisolone and prednisolone concentration by high-performance liquid chromatography.
Corticosteroid concentrations were normalized to urea concentrations in plasma and BALF. Generally, BALF corticosteroid concentration increased as plasma concentration increased. At plasma concentrations greater than 800 ng/ml, BALF methylprednisolone concentrations increased exponentially, whereas the increase for prednisolone remained linear.
BALF methylprednisolone was five times as high as that of prednisolone when plasma corticosteroid concentration was in the 2000 ng/ml range. With this continuous infusion technique, methylprednisolone has a higher degree of bronchoalveolar penetration than prednisolone, and these differences are greater at higher plasma concentrations.
J Allergy Clin Immunol. 1989 Dec;84(6 Pt 1):867-73.
Penetration of corticosteroids into the lung: evidence for a
difference between methylprednisolone and prednisolone.
Vichyanond P1, Irvin CG, Larsen GL, Szefler SJ, Hill MR.Author information
Abstract
Little is known about the penetration of corticosteroids, such as methylprednisolone and prednisolone, into the lung, despite their common use in the treatment of inflammatory lung diseases. To compare methylprednisolone and prednisolone concentrations in the bronchoalveolar space, we administered these two corticosteroids in a randomized, crossover fashion to 17 adult rabbits.
A loading dose was administered and was followed by a continuous infusion for 180 minutes to achieve steady-state plasma concentrations between 200 to 2000 ng/ml. Serial plasma samples were obtained during the infusions. Bronchoalveolar lavages (BAL) were performed at 180 minutes with sterile saline. Plasma and BAL fluid (BALF) were assayed for methylprednisolone and prednisolone concentration by high-performance liquid chromatography.
Corticosteroid concentrations were normalized to urea concentrations in plasma and BALF. Generally, BALF corticosteroid concentration increased as plasma concentration increased. At plasma concentrations greater than 800 ng/ml, BALF methylprednisolone concentrations increased exponentially, whereas the increase for prednisolone remained linear.
BALF methylprednisolone was five times as high as that of prednisolone when plasma corticosteroid concentration was in the 2000 ng/ml range. With this continuous infusion technique, methylprednisolone has a higher degree of bronchoalveolar penetration than prednisolone, and these differences are greater at higher plasma concentrations.
Eczema, Hives, Skin Conditions
http://vitalitymagazine.com/article/natural-alternatives-to-cortisone/
NATURAL ALTERNATIVES TO CORTISONE
(Part IV of a Series on 'Drugs You May Not Need')
by Dr. Zoltan P. Rona, MD, M.Sc.
DR. RONA IS AUTHOR OF VITAMIN D THE SUNSHINE VITAMIN & CO-AUTHOR OF COMPLETE CANDIDA YEAST GUIDEBOOK
“Nearly all men die of their medicines, not of their diseases.” - J.B. Moliere, French playwright
The massive heart attack which took the life of former finance minister, Jim Flaherty, on April 10 has focused public attention on the potential dangers of prednisone. Back in January 2013, in response to increasing public concern about Flaherty’s bloated appearance and facial redness, a spokesman for the minister had stated: “Minister Flaherty is undergoing treatment for a non-life-threatening but serious dermatological condition known as Bullous Pemphigoid. To help clear up the condition the Minister has been prescribed a steroid called Prednisone. This treatment has side effects such as bloating, weight gain, redness in the face, and bouts of sleeplessness.”
Related Articles
Bullous Pemphigoid is a skin disease which causes the immune system to produce antibodies that attack the body, triggering large painful blisters on the arms, legs, and back. The conventional medical treatment utilizes a powerful steroid called Prednisone, which works to clear the lesions from the skin, giving the patient relief from discomfort, pain, and itching.
Prednisone is a synthetic corticosteroid used widely for numerous acute and chronic inflammatory conditions like asthma, temporal arteritis, autoimmune diseases (ie. Bullous Pemphigoid, Crohn’s disease) and numerous skin conditions (especially eczema and hives). Its basic effect is to suppress the immune system’s natural inflammatory response.
While often lifesaving in the short term, prednisone is associated with serious side effects in the long term such as cataracts, high blood pressure, atherosclerosis (hardening of the arteries), fluid retention, osteoporosis, fractures, infections, adrenal disease, and numerous metabolic disorders. In my practice I’ve seen some patients develop diabetes, angina, and heart attacks as a result of long-term use.
Those who use prednisone daily for months or years tend to gain weight and appear puffy-faced and hump-backed. They also develop ulcers requiring more drugs to suppress acid in the stomach, and complain of all manner of digestive disorders. As with most drugs, prednisone is likely to cause a great deal of damage when used long term for any reason.
With the exception of the famous Dr. W. Gifford-Jones, few have questioned the use of Prednisone or suggested safer alternatives to deal with severe skin diseases. So are there effective alternatives to this highly toxic drug? What might have been this unfortunate man’s other options? Is there any evidence supporting the use of a natural anti-inflammatory diet and supplements?
Natural Anti-Inflammatory Approaches
The nice thing about the natural interventions which can be used to reduce or even reverse chronic inflammation is that you can implement them even if you are currently using Prednisone.
And it is even possible to wean off Prednisone safely if you are willing to make some changes in your diet and lifestyle. For this, you will most likely need the supervision of a health professional who has experience in helping people successfully wean off drugs like Prednisone, replacing it gradually over a period of months with a safer, more natural regime.
To begin removal of inflammation from the body, an anti-inflammatory diet is essential. This means the elimination of grains (especially gluten), sugar, alcohol, allergenic foods, trans fats, aspartame, chemicals, caffeine, and toxic heavy metals. Removing excess iron from the system is especially important in reducing inflammation.
One does not need to have celiac disease to be gluten-intolerant and develop autoimmune disease as a result. A key consideration is how much inflammation is caused in any given person by the consumption of gluten-containing products – once the inflammation reaches a certain level, autoimmune disease kicks in and the steroid drugs are brought out.
If you are unconvinced of the necessity to stop consuming gluten in order to get off Prednisone, read the book Grain Brain by Dr. David Perlmutter. In it, he provides more than adequate documentation for the concept that gluten is behind just about every inflammatory condition known to humans, especially those involving the brain. This includes Alzheimer’s disease, depression, and even psychotic behaviours.
In addition, the book Wheat Belly by Dr. William Davis discusses how gluten causes obesity – in reality a condition that is caused by chronic inflammation.
Furthermore, over the years a variety of authors (Dr. Jonathan Wright, Dr. Andrew Weil, Dr. Alan Gaby, and many others) have shown how gluten is at the bottom of conditions such as rheumatoid arthritis, M.S., Lupus and dozens of other diseases usually treated by Prednisone and assorted immunosuppressive drugs.
There are lab tests that can measure your antibodies against gliadin (the major protein in gluten). If these antibodies are elevated, there’s a very strong chance your inflammatory symptoms will respond well to a gluten-free diet. Just about any MD can order the test for you, so ask your family doctor for help in this.
One clue that you might be sensitive to gluten arises from the fact that gluten-sensitive people absorb fats and fat-soluble vitamins poorly. So, if your blood levels of triglycerides, vitamin A, and D are low despite adequate food and supplement intake, consider that you may have a strong sensitivity or allergy to gluten. Also, people who have osteoporosis or osteopenia, despite adequate calcium and vitamin D intakes, can often reverse the bone mineralization issue by going off gluten. In other words, some cases of osteoporosis are caused by gluten sensitivity.
Beyond gluten, get some kind of food allergy/intolerance testing to discover other inflammation triggers. Food allergies/sensitivities cause the gut lining to become inflamed and consequently many vital minerals are poorly absorbed. This is one of the major reasons why people often do not see any benefits from vitamin and mineral supplements despite ever increasing intakes.
One relatively inexpensive lab test now offered by some drugstores as well as provincial labs is the IgG RAST, a blood test that can measure antibodies to as many as 250 foods. Any doctor can order this test but it is not covered by Medicare and costs between $250 and $350 depending on the number of items tested.
Also, look into the possibility that your gut has a fungal overload problem (dysbiosis, candidiasis, helicobacter pylori infections). These can all also be triggers in the creation of autoimmune disorders.
Live cell microscopy can provide clues to the existence of these microbes in your system.
It is now a well-documented fact that candida (fungal) overgrowth in the gastrointestinal tract increases the rate of allergic responses to foods for any individual. In cases where there is evidence of allergy to 30 or more foods, there should be a strong suspicion that this individual is really suffering from a chronic fungal problem that needs to be addressed first.
Candida infections or overgrowth usually arise from a history of heavy antibiotic use, or the use of various steroids including the birth control pill, along with a high carbohydrate diet.
Also, the resolution of psychological and emotional life traumas that are triggers for chronic inflammation is also highly recommended. My favourite methods for reducing mental and emotional stress include:
– EFT (Emotional Freedom Technique)
– NET (Neuro Emotional Technique)
– Yoga, Qi Gong, tennis, or swimming to exercise the cardiovascular and muscular systems and blow off stress
– Deep breathing and meditation to shift the body into a state of deep relaxation
A word of caution here is warranted:
Do not, under any circumstances, go off prednisone suddenly on your own without medical supervision. Doing so could have dire consequences in the form of strong ‘rebound inflammation’, pain, and a worsening of the disease for which you are taking this drug. Asthmatics, for example, can develop severe breathing crises if taken off prednisone too rapidly without adequate stabilization through natural approaches first.
SupplementsThere are many important nutrients that can be supplemented in high doses to reduce inflammation safely. The most important of these are vitamin D and omega-3 fatty acids (EPA and DHA). The use of omega-6 has to be reduced in order for omega-3 to have maximum benefit.
High dose vitamin C and the amino acid L-lysine can help prevent the rapid atherosclerosis caused by Prednisone, so supplementation of both should be considered at levels of 3000 mg. each or more, daily, in any Prednisone weaning-off program.
Correcting nutrient deficiencies, either through dietary changes or supplements, is important because this allows the body to heal tissues and organs damaged by inflammation. In order to determine what these might be, you will need the help of a natural health care professional.
Effective Natural Anti-Inflammatories
People have often asked me what the most effective supplement is to reduce autoimmune disease inflammation. In my experience, curcumin (an extract of the spice turmeric) is the overall most effective remedy. It has been used successfully for just about every inflammatory condition. The evidence for this is piling up in published research from the world’s medical literature.
Curcumin also appears to be effective at protecting our bodies from the damaging, pro-inflammatory effects of fluoride. At this point, one could write a book detailing all of curcumin’s benefits, but suffice to say it is the single most important alternative supplement to Prednisone. Curcumin also works as an anti-cancer, anti-fungal, antioxidant, anti-Alzheimer’s and anti-depressant agent.
My favourite form of curcumin is the BCM-95 extract of turmeric. It’s 100% natural and has at least 7 times the absorption rate of synthetic versions. It does not require any special additive, natural or otherwise, to enhance absorption and is well tolerated. An effective anti-inflammatory dose of curcumin for most conditions is 1000 mg, three times daily with food. Your natural health care provider may recommend either more or less of that amount for your particular condition.
Also, add the whole spice version of turmeric to your meals throughout the day (either in the powder form or the whole root). The amount of curcumin in turmeric is a small fraction of the spice, but is still worthwhile using in your everyday diet. The only downside is that it may stain your teeth a yellow colour that is difficult to remove but this is a small price to pay for better health.
Another potential
Prednisone alternative is licorice root. It works primarily by preventing the breakdown of the adrenal gland’s own production of cortisol, thus potentiating the body’s natural steroidal anti-inflammatory effects. Unfortunately, licorice root can elevate the blood pressure (just like Prednisone) in certain susceptible individuals. So, this may not be the best alternative for many who suffer from chronic inflammation.
Other Natural Anti-Inflammatories
There are many other natural remedies that help reduce inflammation. Here are some of the most effective:
Serrapeptase – is an enzyme derived from the silkworm that appears to be one of the most potent and effective of all the anti-inflammatory enzymes. In high enough doses, serrapeptase is capable of dissolving atherosclerotic plaque. It can also dissolve a cancer cell’s protective coat, thereby making virtually any chemotherapeutic remedy more effective. Many people use serrapeptase to dissolve excessive mucus so it’s highly effective in alleviating chronic bronchitis and sinusitis, conditions which usually trigger steroid prescriptions from doctors.
Pancreatin – is a type of enzyme extracted from porcine pancreas. When consumed by humans, it can get into the bloodstream very much like serrapeptase and help destroy free radicals and pro-inflammatory compounds. The net effect is a reduction of inflammation, carcinogenesis, and numerous other conditions dependent on inflammation to spread. Brand names you might be familiar with include Wobenzyme and Intenzyme Forte.
Bromelain – is an enzyme derived from pineapple, and is especially useful for relieving tendinitis and healing from most physical injuries. Combined with the other enzymes listed here, you get a remarkable anti-inflammatory benefit.
Ginger – is long known and acknowledged as a highly effective anti-inflammatory remedy that can be especially effective in gastrointestinal ills (any gut inflammatory condition), especially chronic nausea, even in early pregnancy.
If you wish to start an anti-inflammatory program of diet change and supplements, it’s highly recommended you see a natural health care professional to work with you on a personalized plan.
Dr. Zoltan P. Rona practices Complementary Medicine in Toronto and is the medical editor of The Encyclopedia of Natural Healing.
He has also published several Canadian best selling books including Return to The Joy of Health, Vitamin D: The Sunshine Vitamin, and Complete Candida Yeast Guidebook (co-authored with Jeanne Marie Martin). For more of his articles, see www.mydoctor.ca/drzoltanrona
Referencesl On Reversing Chronic Inflammation:
http://vitalitymagazine.com/article/reversing-chronic-inflammation/
l Report in Toronto Star: Drug used to treat Jim Flaherty’s skin disease could lead to high blood pressure. http://tinyurl.com/op64jjy
l On the research regarding curcumin: http://www.ncbi.nlm.nih.gov/pubmed/18324353
l Synthetic versus Natural Curcumin. http://www.nutraingredients-usa.com/Suppliers2/EuroPharma-to-launch-probe-into-synthetic-vs-natural-curcumin
l BCM-95 - Natural, Best Absorbed Curcumin: http://www.lef.org/magazine/mag2007/oct2007_report_curcumin_01.htm
l Jonathan Wright, “The Root Cause of Your Autoimmune Disease”. http://www.faim.org/autoimmune/root-cause-autoimmune-disease.html
l W. Gifford-Jones. The Doctor Game. What Could Have Saved Jim Flaherty? http://tinyurl.com/q3hr34z
l Problems with Prednisone? Dr. Andrew Weil. http://www.drweil.com/drw/u/id/QAA326580
l Dr. Michael T. Murray, Natural Alternatives to Over-the-Counter and Prescription Drugs (New York: William Morrow & Co., Inc.), 1998. 155.
l Dr. Joseph Mercola. Dangers of Prednisone and How to Avoid Them. http://articles.mercola.com/sites/articles/archive/2003/11/05/prednisone-dangers.aspx
l Neuro Emotional Technique: http://centreforheartliving.com/net.html
l Emotional Freedom Technique: http://www.eftfree.net/get-the-eftfree-manual-2/
l Sapone A, Lammers K, et al. Divergence of gut permeability and mucosal gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity. BMC Medicine 2011;9:23
l Nieuwenhuizen WF, Pieters RH, Knippels LM, Jansen MC, Koppelman SJ Is Candida albicans a trigger in the onset of celiac disease? Lancet. 2003 Jun 21;361(9375):2152-4.
l Alan R. Gaby, M.D. Nutritional Medicine. Fritz Perlberg Publishing; Concord, NH 2011. http://www.doctorgaby.com
l Julie Daniluk. Meals That Heal Inflammation. Hay House Inc. Publishers: USA, 2011.
Article Tags: vitality, vitality magazine, dr. zoltan rona, natural alternatives to cortisone, natural alternative to prednisone, natural anti-inflammatories
About the AuthorMore Articles by Dr. Zoltan P. Rona, MD, M.Sc.
Dr. Zoltan P. Rona is a graduate of McGill University Medical School (1977) and has a Master’s Degree in Biochemistry and Clinical Nutrition from the University of Bridgeport in Connecticut (1984). He is past president of The Canadian Holistic Medical Association and author or co-author of 12 books on natural medicine, including three Canadian bestsellers, The Joy of Health (1991), Return to the Joy of Health (1995), and Childhood Illness and The Allergy Connection (1997). His latest book is Vitamin D: The Sunshine Vitamin. He is also co-author with Jeanne Marie Martin of The Complete Candida Yeast Guidebook (1996) and is the medical editor of the Benjamin Franklin Award-winning Encyclopedia of Natural Healing (1998).
He has had a private medical practice in the Toronto area for the past 38 years, has appeared on radio and TV, and lectured extensively in Canada and the U.S. Dr. Rona currently writes regular articles for Vitality magazine and for several websites. Visit his website at: www.tristarnaturals.com
http://vitalitymagazine.com/article/natural-alternatives-to-cortisone/
NATURAL ALTERNATIVES TO CORTISONE
(Part IV of a Series on 'Drugs You May Not Need')
by Dr. Zoltan P. Rona, MD, M.Sc.
DR. RONA IS AUTHOR OF VITAMIN D THE SUNSHINE VITAMIN & CO-AUTHOR OF COMPLETE CANDIDA YEAST GUIDEBOOK
“Nearly all men die of their medicines, not of their diseases.” - J.B. Moliere, French playwright
The massive heart attack which took the life of former finance minister, Jim Flaherty, on April 10 has focused public attention on the potential dangers of prednisone. Back in January 2013, in response to increasing public concern about Flaherty’s bloated appearance and facial redness, a spokesman for the minister had stated: “Minister Flaherty is undergoing treatment for a non-life-threatening but serious dermatological condition known as Bullous Pemphigoid. To help clear up the condition the Minister has been prescribed a steroid called Prednisone. This treatment has side effects such as bloating, weight gain, redness in the face, and bouts of sleeplessness.”
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Bullous Pemphigoid is a skin disease which causes the immune system to produce antibodies that attack the body, triggering large painful blisters on the arms, legs, and back. The conventional medical treatment utilizes a powerful steroid called Prednisone, which works to clear the lesions from the skin, giving the patient relief from discomfort, pain, and itching.
Prednisone is a synthetic corticosteroid used widely for numerous acute and chronic inflammatory conditions like asthma, temporal arteritis, autoimmune diseases (ie. Bullous Pemphigoid, Crohn’s disease) and numerous skin conditions (especially eczema and hives). Its basic effect is to suppress the immune system’s natural inflammatory response.
While often lifesaving in the short term, prednisone is associated with serious side effects in the long term such as cataracts, high blood pressure, atherosclerosis (hardening of the arteries), fluid retention, osteoporosis, fractures, infections, adrenal disease, and numerous metabolic disorders. In my practice I’ve seen some patients develop diabetes, angina, and heart attacks as a result of long-term use.
Those who use prednisone daily for months or years tend to gain weight and appear puffy-faced and hump-backed. They also develop ulcers requiring more drugs to suppress acid in the stomach, and complain of all manner of digestive disorders. As with most drugs, prednisone is likely to cause a great deal of damage when used long term for any reason.
With the exception of the famous Dr. W. Gifford-Jones, few have questioned the use of Prednisone or suggested safer alternatives to deal with severe skin diseases. So are there effective alternatives to this highly toxic drug? What might have been this unfortunate man’s other options? Is there any evidence supporting the use of a natural anti-inflammatory diet and supplements?
Natural Anti-Inflammatory Approaches
The nice thing about the natural interventions which can be used to reduce or even reverse chronic inflammation is that you can implement them even if you are currently using Prednisone.
And it is even possible to wean off Prednisone safely if you are willing to make some changes in your diet and lifestyle. For this, you will most likely need the supervision of a health professional who has experience in helping people successfully wean off drugs like Prednisone, replacing it gradually over a period of months with a safer, more natural regime.
To begin removal of inflammation from the body, an anti-inflammatory diet is essential. This means the elimination of grains (especially gluten), sugar, alcohol, allergenic foods, trans fats, aspartame, chemicals, caffeine, and toxic heavy metals. Removing excess iron from the system is especially important in reducing inflammation.
One does not need to have celiac disease to be gluten-intolerant and develop autoimmune disease as a result. A key consideration is how much inflammation is caused in any given person by the consumption of gluten-containing products – once the inflammation reaches a certain level, autoimmune disease kicks in and the steroid drugs are brought out.
If you are unconvinced of the necessity to stop consuming gluten in order to get off Prednisone, read the book Grain Brain by Dr. David Perlmutter. In it, he provides more than adequate documentation for the concept that gluten is behind just about every inflammatory condition known to humans, especially those involving the brain. This includes Alzheimer’s disease, depression, and even psychotic behaviours.
In addition, the book Wheat Belly by Dr. William Davis discusses how gluten causes obesity – in reality a condition that is caused by chronic inflammation.
Furthermore, over the years a variety of authors (Dr. Jonathan Wright, Dr. Andrew Weil, Dr. Alan Gaby, and many others) have shown how gluten is at the bottom of conditions such as rheumatoid arthritis, M.S., Lupus and dozens of other diseases usually treated by Prednisone and assorted immunosuppressive drugs.
There are lab tests that can measure your antibodies against gliadin (the major protein in gluten). If these antibodies are elevated, there’s a very strong chance your inflammatory symptoms will respond well to a gluten-free diet. Just about any MD can order the test for you, so ask your family doctor for help in this.
One clue that you might be sensitive to gluten arises from the fact that gluten-sensitive people absorb fats and fat-soluble vitamins poorly. So, if your blood levels of triglycerides, vitamin A, and D are low despite adequate food and supplement intake, consider that you may have a strong sensitivity or allergy to gluten. Also, people who have osteoporosis or osteopenia, despite adequate calcium and vitamin D intakes, can often reverse the bone mineralization issue by going off gluten. In other words, some cases of osteoporosis are caused by gluten sensitivity.
Beyond gluten, get some kind of food allergy/intolerance testing to discover other inflammation triggers. Food allergies/sensitivities cause the gut lining to become inflamed and consequently many vital minerals are poorly absorbed. This is one of the major reasons why people often do not see any benefits from vitamin and mineral supplements despite ever increasing intakes.
One relatively inexpensive lab test now offered by some drugstores as well as provincial labs is the IgG RAST, a blood test that can measure antibodies to as many as 250 foods. Any doctor can order this test but it is not covered by Medicare and costs between $250 and $350 depending on the number of items tested.
Also, look into the possibility that your gut has a fungal overload problem (dysbiosis, candidiasis, helicobacter pylori infections). These can all also be triggers in the creation of autoimmune disorders.
Live cell microscopy can provide clues to the existence of these microbes in your system.
It is now a well-documented fact that candida (fungal) overgrowth in the gastrointestinal tract increases the rate of allergic responses to foods for any individual. In cases where there is evidence of allergy to 30 or more foods, there should be a strong suspicion that this individual is really suffering from a chronic fungal problem that needs to be addressed first.
Candida infections or overgrowth usually arise from a history of heavy antibiotic use, or the use of various steroids including the birth control pill, along with a high carbohydrate diet.
Also, the resolution of psychological and emotional life traumas that are triggers for chronic inflammation is also highly recommended. My favourite methods for reducing mental and emotional stress include:
– EFT (Emotional Freedom Technique)
– NET (Neuro Emotional Technique)
– Yoga, Qi Gong, tennis, or swimming to exercise the cardiovascular and muscular systems and blow off stress
– Deep breathing and meditation to shift the body into a state of deep relaxation
A word of caution here is warranted:
Do not, under any circumstances, go off prednisone suddenly on your own without medical supervision. Doing so could have dire consequences in the form of strong ‘rebound inflammation’, pain, and a worsening of the disease for which you are taking this drug. Asthmatics, for example, can develop severe breathing crises if taken off prednisone too rapidly without adequate stabilization through natural approaches first.
SupplementsThere are many important nutrients that can be supplemented in high doses to reduce inflammation safely. The most important of these are vitamin D and omega-3 fatty acids (EPA and DHA). The use of omega-6 has to be reduced in order for omega-3 to have maximum benefit.
High dose vitamin C and the amino acid L-lysine can help prevent the rapid atherosclerosis caused by Prednisone, so supplementation of both should be considered at levels of 3000 mg. each or more, daily, in any Prednisone weaning-off program.
Correcting nutrient deficiencies, either through dietary changes or supplements, is important because this allows the body to heal tissues and organs damaged by inflammation. In order to determine what these might be, you will need the help of a natural health care professional.
Effective Natural Anti-Inflammatories
People have often asked me what the most effective supplement is to reduce autoimmune disease inflammation. In my experience, curcumin (an extract of the spice turmeric) is the overall most effective remedy. It has been used successfully for just about every inflammatory condition. The evidence for this is piling up in published research from the world’s medical literature.
Curcumin also appears to be effective at protecting our bodies from the damaging, pro-inflammatory effects of fluoride. At this point, one could write a book detailing all of curcumin’s benefits, but suffice to say it is the single most important alternative supplement to Prednisone. Curcumin also works as an anti-cancer, anti-fungal, antioxidant, anti-Alzheimer’s and anti-depressant agent.
My favourite form of curcumin is the BCM-95 extract of turmeric. It’s 100% natural and has at least 7 times the absorption rate of synthetic versions. It does not require any special additive, natural or otherwise, to enhance absorption and is well tolerated. An effective anti-inflammatory dose of curcumin for most conditions is 1000 mg, three times daily with food. Your natural health care provider may recommend either more or less of that amount for your particular condition.
Also, add the whole spice version of turmeric to your meals throughout the day (either in the powder form or the whole root). The amount of curcumin in turmeric is a small fraction of the spice, but is still worthwhile using in your everyday diet. The only downside is that it may stain your teeth a yellow colour that is difficult to remove but this is a small price to pay for better health.
Another potential
Prednisone alternative is licorice root. It works primarily by preventing the breakdown of the adrenal gland’s own production of cortisol, thus potentiating the body’s natural steroidal anti-inflammatory effects. Unfortunately, licorice root can elevate the blood pressure (just like Prednisone) in certain susceptible individuals. So, this may not be the best alternative for many who suffer from chronic inflammation.
Other Natural Anti-Inflammatories
There are many other natural remedies that help reduce inflammation. Here are some of the most effective:
Serrapeptase – is an enzyme derived from the silkworm that appears to be one of the most potent and effective of all the anti-inflammatory enzymes. In high enough doses, serrapeptase is capable of dissolving atherosclerotic plaque. It can also dissolve a cancer cell’s protective coat, thereby making virtually any chemotherapeutic remedy more effective. Many people use serrapeptase to dissolve excessive mucus so it’s highly effective in alleviating chronic bronchitis and sinusitis, conditions which usually trigger steroid prescriptions from doctors.
Pancreatin – is a type of enzyme extracted from porcine pancreas. When consumed by humans, it can get into the bloodstream very much like serrapeptase and help destroy free radicals and pro-inflammatory compounds. The net effect is a reduction of inflammation, carcinogenesis, and numerous other conditions dependent on inflammation to spread. Brand names you might be familiar with include Wobenzyme and Intenzyme Forte.
Bromelain – is an enzyme derived from pineapple, and is especially useful for relieving tendinitis and healing from most physical injuries. Combined with the other enzymes listed here, you get a remarkable anti-inflammatory benefit.
Ginger – is long known and acknowledged as a highly effective anti-inflammatory remedy that can be especially effective in gastrointestinal ills (any gut inflammatory condition), especially chronic nausea, even in early pregnancy.
If you wish to start an anti-inflammatory program of diet change and supplements, it’s highly recommended you see a natural health care professional to work with you on a personalized plan.
Dr. Zoltan P. Rona practices Complementary Medicine in Toronto and is the medical editor of The Encyclopedia of Natural Healing.
He has also published several Canadian best selling books including Return to The Joy of Health, Vitamin D: The Sunshine Vitamin, and Complete Candida Yeast Guidebook (co-authored with Jeanne Marie Martin). For more of his articles, see www.mydoctor.ca/drzoltanrona
Referencesl On Reversing Chronic Inflammation:
http://vitalitymagazine.com/article/reversing-chronic-inflammation/
l Report in Toronto Star: Drug used to treat Jim Flaherty’s skin disease could lead to high blood pressure. http://tinyurl.com/op64jjy
l On the research regarding curcumin: http://www.ncbi.nlm.nih.gov/pubmed/18324353
l Synthetic versus Natural Curcumin. http://www.nutraingredients-usa.com/Suppliers2/EuroPharma-to-launch-probe-into-synthetic-vs-natural-curcumin
l BCM-95 - Natural, Best Absorbed Curcumin: http://www.lef.org/magazine/mag2007/oct2007_report_curcumin_01.htm
l Jonathan Wright, “The Root Cause of Your Autoimmune Disease”. http://www.faim.org/autoimmune/root-cause-autoimmune-disease.html
l W. Gifford-Jones. The Doctor Game. What Could Have Saved Jim Flaherty? http://tinyurl.com/q3hr34z
l Problems with Prednisone? Dr. Andrew Weil. http://www.drweil.com/drw/u/id/QAA326580
l Dr. Michael T. Murray, Natural Alternatives to Over-the-Counter and Prescription Drugs (New York: William Morrow & Co., Inc.), 1998. 155.
l Dr. Joseph Mercola. Dangers of Prednisone and How to Avoid Them. http://articles.mercola.com/sites/articles/archive/2003/11/05/prednisone-dangers.aspx
l Neuro Emotional Technique: http://centreforheartliving.com/net.html
l Emotional Freedom Technique: http://www.eftfree.net/get-the-eftfree-manual-2/
l Sapone A, Lammers K, et al. Divergence of gut permeability and mucosal gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity. BMC Medicine 2011;9:23
l Nieuwenhuizen WF, Pieters RH, Knippels LM, Jansen MC, Koppelman SJ Is Candida albicans a trigger in the onset of celiac disease? Lancet. 2003 Jun 21;361(9375):2152-4.
l Alan R. Gaby, M.D. Nutritional Medicine. Fritz Perlberg Publishing; Concord, NH 2011. http://www.doctorgaby.com
l Julie Daniluk. Meals That Heal Inflammation. Hay House Inc. Publishers: USA, 2011.
Article Tags: vitality, vitality magazine, dr. zoltan rona, natural alternatives to cortisone, natural alternative to prednisone, natural anti-inflammatories
About the AuthorMore Articles by Dr. Zoltan P. Rona, MD, M.Sc.
Dr. Zoltan P. Rona is a graduate of McGill University Medical School (1977) and has a Master’s Degree in Biochemistry and Clinical Nutrition from the University of Bridgeport in Connecticut (1984). He is past president of The Canadian Holistic Medical Association and author or co-author of 12 books on natural medicine, including three Canadian bestsellers, The Joy of Health (1991), Return to the Joy of Health (1995), and Childhood Illness and The Allergy Connection (1997). His latest book is Vitamin D: The Sunshine Vitamin. He is also co-author with Jeanne Marie Martin of The Complete Candida Yeast Guidebook (1996) and is the medical editor of the Benjamin Franklin Award-winning Encyclopedia of Natural Healing (1998).
He has had a private medical practice in the Toronto area for the past 38 years, has appeared on radio and TV, and lectured extensively in Canada and the U.S. Dr. Rona currently writes regular articles for Vitality magazine and for several websites. Visit his website at: www.tristarnaturals.com
The Best Natural Alternatives to Prednisone
http://health.onehowto.com/article/the-best-natural-alternatives-to-prednisone-9912.html
Max. D Gray
Prednisone is a corticosteroid drug used mainly to treat some inflammatory diseases such as asthma and crohn's disease. Besides this major use, it is also prescribed to treat some autoimmune diseases and even in some cases cancer. The drug is widely used for its immunosuppressant properties, i.e. preventing the activity of the immune system, but the truth is that it has many side effects harmful for the body. The prolongued use of this drug can be detrimental for our health, so it is important to know which alternatives we can take to help ease the pain in an alternative way.
You must consult your doctor if you want to replace Prednisone with natural remedies. Under no circumstances you should stop your treatment and replace the drug for other remedies without the supervision of a professional. However, if you want more information on which alternatives could work better for you, in this OneHowTo article we explain the best natural alternatives to Prednisone.
Contents
What is Prednisone used for?Prednisone is a corticosteroid drug used to treat inflammatory diseases, autoimmune diseases and, when taken in high doses, even cancer. These are some of the most common diseases treated with Prednisone:
What are the side effects of Prednisone Prednisone is an effective drug to treat the diseases mentioned above, but it is associated with many side effects. Some of the most important are:
These side effects can make the life of the person taking the drug much difficult, and for this reason some people want to try alternative remedies to Prednisone. However, it is important to bear in mind that no alternative will work as fast and effectively as Prednisone.
When choosing the best alternative to Prednisone it is important to know for which condition you're taking it for, as some remedies might work better than others.
Prednisone alternatives to treat inflammatory diseases If you're taking Prednisone to treat inflammatory diseases such as asthma, arthritis and inflammatory bowel syndrome, there are a series of alternatives that can help you with your problem.
An anti-inflammatory diet is the first step to treat this problem naturally. To carry an anti-inflammatory diet you should eliminate all grains (including gluten), sugar, alcohol, trans fats, aspartane, caffeine and chemicals. A dietician will be able to create a complete anti-inflammatory diet according to your needs.
In addition to the anti-inflammatory diet you can take other anti-inflammatory herbs and supplements that will help you fight off your ailment:
It is recommended to start taking these while you're still taking Prednisone. You can then gradually decrease your intake of the drug until the point in which you might not need it anymore. However, we remind you that you must visit a doctor before replacing Prednisone with any natural remedy.
Prednisone alternatives to treat migraines If you're taking Prednisone to treat your migraines, you can replace the drug for some natural remedies that might ease your pain. Chamomile, white willow black tea and essential oils are great if you want to avoid migraines. These terrible headaches can be treated with herbs and are possible to relieve at home if you follow some steps.
Chinese medicine as an alternative to Prednisone Some herbal remedies from traditional Chinese medicine can work to treat the diseases for which Prednisone is used for. Especially in the case of treating asthma, some studies have determined that a Chinese herbal compound called ASHMI can work without the side effects that Prednisone would cause.
Traditional Chinese medicine has also studied the effects of natural compounds to treat allergies and have found out that a compound called FAHF-2 could work.
If you want to try traditional Chinese medicine you should put yourself in the hands of a certified professional. Be aware that sometimes people pretend to be natural healers but they don't have the necessary education. Always check references before trusting any natural healer.
Never replace Prednisone without the supervision of a professionalThere are natural alternatives available to replace Prednisone, but you should never do it without the supervision of your doctor. If the side effects of Prednisone are making your life too difficult the best you can do is speak with your doctor and he/she will tell you what is the best alternative to take depending on your illness. Never do it on your own as there could be severe complications.
If you would like more information on alternative remedies for synthetic drugs, read this article and find out the best natural alternatives to Omeprazole.
This article is merely informative, OneHowTo does not have the authority to prescribe any medical treatments or create a diagnosis. We invite you to visit your doctor if you have any type of condition or pain.
If you want to read similar articles to The Best Natural Alternatives to Prednisone, we recommend you visit our Drugs & supplements category.
http://health.onehowto.com/article/the-best-natural-alternatives-to-prednisone-9912.html
Max. D Gray
Prednisone is a corticosteroid drug used mainly to treat some inflammatory diseases such as asthma and crohn's disease. Besides this major use, it is also prescribed to treat some autoimmune diseases and even in some cases cancer. The drug is widely used for its immunosuppressant properties, i.e. preventing the activity of the immune system, but the truth is that it has many side effects harmful for the body. The prolongued use of this drug can be detrimental for our health, so it is important to know which alternatives we can take to help ease the pain in an alternative way.
You must consult your doctor if you want to replace Prednisone with natural remedies. Under no circumstances you should stop your treatment and replace the drug for other remedies without the supervision of a professional. However, if you want more information on which alternatives could work better for you, in this OneHowTo article we explain the best natural alternatives to Prednisone.
Contents
- What is Prednisone used for?
- What are the side effects of Prednisone
- Prednisone alternatives to treat inflammatory diseases
- Prednisone alternatives to treat migraines
- Chinese medicine as an alternative to Prednisone
- Never replace Prednisone without the supervision of a professional
What is Prednisone used for?Prednisone is a corticosteroid drug used to treat inflammatory diseases, autoimmune diseases and, when taken in high doses, even cancer. These are some of the most common diseases treated with Prednisone:
- Asthma
- Arthritis
- Rheumatic disorders
- Urticaria
- Inflammatory bowel
- Migraines
- Some allergies
- Eye problems
- Immune system disorders
- Blood disorders
- Breathing problems
What are the side effects of Prednisone Prednisone is an effective drug to treat the diseases mentioned above, but it is associated with many side effects. Some of the most important are:
- High blood glucose levels
- Depression and anxiety
- Osteoporosis
- Glaucoma
- Cataracts
- Heart problems
- Trouble sleeping
- Heartburn
- Nausea and vomiting
- Cushing's syndrome
These side effects can make the life of the person taking the drug much difficult, and for this reason some people want to try alternative remedies to Prednisone. However, it is important to bear in mind that no alternative will work as fast and effectively as Prednisone.
When choosing the best alternative to Prednisone it is important to know for which condition you're taking it for, as some remedies might work better than others.
Prednisone alternatives to treat inflammatory diseases If you're taking Prednisone to treat inflammatory diseases such as asthma, arthritis and inflammatory bowel syndrome, there are a series of alternatives that can help you with your problem.
An anti-inflammatory diet is the first step to treat this problem naturally. To carry an anti-inflammatory diet you should eliminate all grains (including gluten), sugar, alcohol, trans fats, aspartane, caffeine and chemicals. A dietician will be able to create a complete anti-inflammatory diet according to your needs.
In addition to the anti-inflammatory diet you can take other anti-inflammatory herbs and supplements that will help you fight off your ailment:
- Curcumin (extract of Turmeric). It is one of the most important alternative supplement to Prednisone that has anti-inflammatory, antioxidant and chemopreventive properties. Turmeric is especially used to treat arthritis.
- Liquorice root. It prevents the breakdown of the adrenal gland that produces cortisol and it strengthens the body's natural anti-inflammatory effects. However, liquorice root can elevate blood pressure, so it's important to avoid it if you suffer from this condition.
- Ginger. It is a really good natural anti-inflammatory.
It is recommended to start taking these while you're still taking Prednisone. You can then gradually decrease your intake of the drug until the point in which you might not need it anymore. However, we remind you that you must visit a doctor before replacing Prednisone with any natural remedy.
Prednisone alternatives to treat migraines If you're taking Prednisone to treat your migraines, you can replace the drug for some natural remedies that might ease your pain. Chamomile, white willow black tea and essential oils are great if you want to avoid migraines. These terrible headaches can be treated with herbs and are possible to relieve at home if you follow some steps.
Chinese medicine as an alternative to Prednisone Some herbal remedies from traditional Chinese medicine can work to treat the diseases for which Prednisone is used for. Especially in the case of treating asthma, some studies have determined that a Chinese herbal compound called ASHMI can work without the side effects that Prednisone would cause.
Traditional Chinese medicine has also studied the effects of natural compounds to treat allergies and have found out that a compound called FAHF-2 could work.
If you want to try traditional Chinese medicine you should put yourself in the hands of a certified professional. Be aware that sometimes people pretend to be natural healers but they don't have the necessary education. Always check references before trusting any natural healer.
Never replace Prednisone without the supervision of a professionalThere are natural alternatives available to replace Prednisone, but you should never do it without the supervision of your doctor. If the side effects of Prednisone are making your life too difficult the best you can do is speak with your doctor and he/she will tell you what is the best alternative to take depending on your illness. Never do it on your own as there could be severe complications.
If you would like more information on alternative remedies for synthetic drugs, read this article and find out the best natural alternatives to Omeprazole.
This article is merely informative, OneHowTo does not have the authority to prescribe any medical treatments or create a diagnosis. We invite you to visit your doctor if you have any type of condition or pain.
If you want to read similar articles to The Best Natural Alternatives to Prednisone, we recommend you visit our Drugs & supplements category.
http://www.medhelp.org/posts/Adrenal-Insufficiency/why-prednisone-and-not-hydrocortisone/show/922448
Communities>Adrenal Insufficiency>why prednisone and not hydrocortisone?
Aa
a question
why prednisone and not hydrocortisone?
jdrtwin1
I was just wondering why my doc has me on prednisone for my adrenal insufficiancy and not hydrocortisone?
Apr 12, 2009
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clear signs of insufficiency but normal cortisol?!
penny3323
Hi, I recently got my morning cortisol level tested because I have suspected for a while that my adrenals are fatigued. I have been in a re...
Sep 12, 2013
Prednisone Use for Over a Year
gale569
I have been on Prednisone for almost a year due to chronic pericarditis from an ablation procedure for PVC's. During the procedure , my hear...
Mar 07, 2010
Body temp regulation is difficult
hati
Thought I might be in crisis. I switched back from hydrocortisone to prednisone. One symptom, is that I can't seem to keep my body temperat...
Jun 20, 2010
22 Answers
Page 1 of 1
stella5349
Well it does have most of the same components for adrenal repair as HC does - but the side effects of Pred are icky as far as I am concerned.
Apr 15, 2009
Upvote - 0
jdrtwin1
they are icky...i've gained 20lbs in 5 months, grown facial hair and haven't had a good night's sleep in months which has led to depression and anxiety issues.
Apr 15, 2009
Upvote - 0
rumpled
Pred is a medium acting, long term steroid. It has a long half life. It can last longer than a day. So the body never rests - hence more side effects.
HC is a short term, fast acting steroid. It has a short half life. It allows the body to more closely mimic the natural diurnal rhythm if taken correctly (I will say, it is inconvenient) and is more like what the body makes itself.
They have finally developed a long acting HC,
duocort,
that will be available sometime soon and it will mimic the diurnal rhythm without the side effects of pred - so once a day dosing.
Look for a steroid calculator and you can see what I mean about half lives and all.
Apr 17, 2009
Upvote - 0
boochay
I am on 20 mg prednisone for a year and hate it . my blood work still comes up low cortisol .
any idea if that is normal if you are on prednisone? does this mean I need more steroid?
can you detox off prednisone with hydr cortisone or corteff?
Apr 25, 2009
Upvote - 0
jabele
yaeh, that seems excessive. You don't want to be on that much steroids if you don't ABSOLUTELY need to be because steroids are an immunosuppressant. I've having trouble w/ that taking 20mg a day of hydrocortisone which is less potent than pred.
Jun 08, 2009
Upvote - 0
rumpled
20mg of HC = 5mg of pred so your doc has you on 4 times the normal dose that a body needs. 20mgs is around what a normal person takes. Unless you have other health problems that require you to need more pred, you are eating your bones, muscle, eyes etc. It may not happen today - but it will happen in the future.
Why your blood work comes up low could be timing (pred takes a few hours to kick in, hence why it is not used in an emergency but with the half life, you stack dosing, another reason it is not great), lab error, or it can depend on what tests you are doing.
Jun 14, 2009
Upvote - 0
quizshow904
I have adrenal insufficiency(as of 3 months ago) and just went from 25mg / day of hydrocortisone to 5 mg of prednisone. This is long term, at least 6 months, till we run tests again. My Endo feels that I was miss diagnosed as having Addison's. We'll see.
Dec 04, 2009
Upvote - 0
inwardgranny
i'm taking both 40mg of predisone in the morning and 20mg of hydrocortisone at night. is there a reason why you can't take them both. i also have meniere ear which the predisone helps and my seg rate is high so i might have some other autoimmune disease. but i know this is working for me. i'm not swelling anymore taking them both.
Jun 28, 2010
Upvote - 0
rumpled
Well, you can take them both but it is very very hard on the body. Your 40mg is pretty high - as said before, 5mg is enough to shut down and replace adrenal function. Pred lasts 24-36 hours, so I am not sure why your doc is making you take HC at night unless he really really does not want you to sleep? A person who takes HC to live, like me, avoids taking HC anywhere in the afternoon so that they can sleep - the body needs to have a period of time off steroids to repair muscle, bones, etc.
I would get a dexa scan and monitor your bones.
DEXA SCAN ...
Usually pred is prescribed in the case of diseases like arthritis, ms, asthma, etc. where you need anti-inflammatory action to last. As you do not appear to be developing Cushing's symptoms, you must be *using* the steroid but many of the effects may be hidden in your eyes, bones and muscles.
Jun 28, 2010
Upvote - 0
mk549
I was diagnosed with adrenal insufficiency and a ruptured pituatiary tumor early this spring. I feel very weak if I take anything less than 40 mg. of cortisol. Is this comparable what other take -- noting that I do have chronic pain from the tumor which may elevate my need?
Jul 13, 2010
Upvote - 0
rumpled
Pain is not usually treated with HC unless the source is inflammatory (ie arthritis) so... taking 40mg may be giving you the steroid *boost* and in turn, wrecking your body's bones and muscles...
Have you taken a UFC or other testing to see how your body is using that steroid? You do the urinary free cortisol test on meds, to see how you are - and you should be in mid-range.
Jul 14, 2010
Upvote - 0
Lucy96
Im on 5mg of pred for sarcordosis of the lungs ive been slowly coming off the pred for 2 and half years and have every side effect. My endo wants me to start taking 15mg of HC in the morning and 5mg at 5:00pm....to see if i feel better and have more energy...
As of now i sleep about 12-14 hours a day. Just wanted to know if this is a good idea or just stick to the pred...my lung doc said i could come down to 2.5mg of pred and see how i do.
Just want some input...Thanks
Aug 16, 2010
Upvote - 0
rumpled
You are taking pred for your lungs so you have a reason for it, however, it seems that your side effects show that your body is not liking it.
If you can cut to 2.5mg pred, think of this, pred takes about 4 hours to kick in, and can last up to 36 hours (hence the side effects), HC kicks in pretty much right away, but only lasts about 6 hours. That 5pm dose may or may not, depending on you, cause sleep issues. Most endos advise dosing no later than 2 or 3pm but some people need a 2.5mg HC at night to sleep. It happens.
You may be sleeping so much as you may have a case of steroid-induced Cushing's - it causes fatigue. It does a number in the muscles and has a lot of other hidden side effects. 5mg =20mg HC, so to just take the 2.5 pred would put you under a suppressive dose, and force your adrenals to work, if it in fact they could, and if you have been on steroids a long time, well, they may not. That could be a dangerous situation. To get out of the Cushing's, you need to drop the pred, but it is going to hurt to get back and force yourself back, as you know, weaning bites.
So that is food for thought... I cannot make the decision - you could alternate days since pred lasts so long though... that is one way to help wean. You may also need more HC in the wean since the pred lasts longer, it acts like more. Just ideas.
Aug 17, 2010
Upvote - 0
allmymarbles
I am confused. It was prednisone that gave me adrenal fatigue.
Aug 28, 2010
Upvote - 0
rumpled
Yes - alas, pred can give AI, but in Lucy (and maybe you, I can't recall your history) she was taking the pred for a lung disorder.
Some docs give pred, dex or HC to treat AI - it can depend on the patient, the doc, the activity or the other diseases the person has...
If a person takes large doses of a suppressive corticosteroid... some lose the adrenals, some don't. Bodies are weird that way.
Aug 29, 2010
Upvote - 0
allmymarbles
I had a lung disorder too. It seems to me that the endocrine system is still little understood.
Aug 29, 2010
Upvote - 0
Brucergoldberg
Hey Rumpled,
This is a really old post but i am starting to explore taking predisone and possibly hydrocortisone because i am having a hard time tolerating the levothyroxine.
I wanted to ask you, people speak of 2.5 mg and 1mg of predisone. That is a tiny tiny amount, correct? The smallest dose that could be prescribed is .10. So how does someone take 2.5? 1?
I feel like my adrenals are kicking in and producing excess adrenaline in response to the levo, or hypothyroidism..
bruce
Nov 13, 2010
Upvote - 0
rumpled
I am not a proponent of the "thyroid and adrenal" thing - I take both medications, have for years... the only stuff I have read on it is not on medical sites but other and I respectfully just don't follow those thoughts. If you need thyroid, you need, it but you may be on the wrong dose?
If you feel buzzed, then perhaps, the the pred is giving you a buzz of cortisol. If you look up a corticosteroid calculator, you will see that pred lasts a long time - it also takes about 4 hours to kick in. So when you take pred, you basically stack doses. Pred is not given in emergencies for that reason.
I don't know anything about any adrenaline response - I would think it is racing heart for too much thyroid or too much pred.
I would guess to take 2.5 you take a whole bunch of pills or do a bunch of cutting of larger pills.
Nov 14, 2010
Upvote - 0
tgcieri
Hi Lucy....I too have Sarcoidosis...have for 20 years...also have Gastro Paresis, Chrones and I get granulomas in my sinues (had 5 surgeries already and number 6 is being scheduled)... (auto immune diseases love me). I found when they took me off the Prednisone and put me on the Hydrocortisone....everyone was ignoring my other issues. I have a "smoking cough" (never smoked) that has been lingering for 3 months now....I have Chronic Bronchitus (COPD) so my pulmonary doctor is not happy....they just put me back on prednisone...and stopped the Hydrocortisone...until I am through the Prednisone regiment. I feel better on Prednisone! I do watch what I eat all the time...I find on the Hydrocortisone I am ALWAYS looking to put something in mouth....hold water weight...and gained a lot more weight than I did on Prednisone. I am going to talk to my endo doctor about staying on Prednisone...they have to consider all my other issues....I don't think the Hydrocortisone is a fixer for Sarcoidosis....we need something that stays in the body...I was told the Hydrocortisone is only a 4 hour fix per pill...which means (for me) on 3 a day....I am only being covered for 12 of the 24 hours..... hope this gives you some answers...everyone is different...but you probably need to talk to your pulmonary and endo doctors...or have them talk to each other....good luck!
Mar 23, 2012
Upvote - 0
Bones1970
I have Adrenal insuffiency and Chronic Cluster headaches. I am no longer on HC or Pred and now my headaches flare up longer and more often. The treatment calls for 10ltr of oxygen and 60 mg of prednisone. Prednisone caused my Arenal problems. Confused with 24/7/365 headaches
Oct 26, 2012
Upvote - 0
rumpled
Are you still on the pred? It is confusing since you say you are not, but your treatment calls for it? If you stopped and you have AI, you probably have a headache as you are in a LOW - in other words you need some sort of replacement for cortisol.
I get massive headaches when I don't have enough cortisol.
Oct 27, 2012
Upvote - 0
lesnmike
From what we were told by our endocrinologist, if you are taking the medication for Addison's Disease (or adrenal insufficiancy) you will not get the side affects of weight gain,moon face, etc. because your body is so low on the cortisol that by taking the oral meds is bringing your body up to normal, when these side affects ususlly happen, it is from an overamount of cortisol in your body, such as taking it for asthma, arthritis, etc.
Sep 13, 2013
Upvote - 0
Aa
a question
why prednisone and not hydrocortisone?
jdrtwin1
I was just wondering why my doc has me on prednisone for my adrenal insufficiancy and not hydrocortisone?
Apr 12, 2009
Follow
Upvote - 0
22 Answers
Next Question
Related Questions
clear signs of insufficiency but normal cortisol?!
penny3323
Hi, I recently got my morning cortisol level tested because I have suspected for a while that my adrenals are fatigued. I have been in a re...
Sep 12, 2013
Prednisone Use for Over a Year
gale569
I have been on Prednisone for almost a year due to chronic pericarditis from an ablation procedure for PVC's. During the procedure , my hear...
Mar 07, 2010
Body temp regulation is difficult
hati
Thought I might be in crisis. I switched back from hydrocortisone to prednisone. One symptom, is that I can't seem to keep my body temperat...
Jun 20, 2010
22 Answers
Page 1 of 1
stella5349
Well it does have most of the same components for adrenal repair as HC does - but the side effects of Pred are icky as far as I am concerned.
Apr 15, 2009
Upvote - 0
jdrtwin1
they are icky...i've gained 20lbs in 5 months, grown facial hair and haven't had a good night's sleep in months which has led to depression and anxiety issues.
Apr 15, 2009
Upvote - 0
rumpled
Pred is a medium acting, long term steroid. It has a long half life. It can last longer than a day. So the body never rests - hence more side effects.
HC is a short term, fast acting steroid. It has a short half life. It allows the body to more closely mimic the natural diurnal rhythm if taken correctly (I will say, it is inconvenient) and is more like what the body makes itself.
They have finally developed a long acting HC,
duocort,
that will be available sometime soon and it will mimic the diurnal rhythm without the side effects of pred - so once a day dosing.
Look for a steroid calculator and you can see what I mean about half lives and all.
Apr 17, 2009
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boochay
I am on 20 mg prednisone for a year and hate it . my blood work still comes up low cortisol .
any idea if that is normal if you are on prednisone? does this mean I need more steroid?
can you detox off prednisone with hydr cortisone or corteff?
Apr 25, 2009
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jabele
yaeh, that seems excessive. You don't want to be on that much steroids if you don't ABSOLUTELY need to be because steroids are an immunosuppressant. I've having trouble w/ that taking 20mg a day of hydrocortisone which is less potent than pred.
Jun 08, 2009
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rumpled
20mg of HC = 5mg of pred so your doc has you on 4 times the normal dose that a body needs. 20mgs is around what a normal person takes. Unless you have other health problems that require you to need more pred, you are eating your bones, muscle, eyes etc. It may not happen today - but it will happen in the future.
Why your blood work comes up low could be timing (pred takes a few hours to kick in, hence why it is not used in an emergency but with the half life, you stack dosing, another reason it is not great), lab error, or it can depend on what tests you are doing.
Jun 14, 2009
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quizshow904
I have adrenal insufficiency(as of 3 months ago) and just went from 25mg / day of hydrocortisone to 5 mg of prednisone. This is long term, at least 6 months, till we run tests again. My Endo feels that I was miss diagnosed as having Addison's. We'll see.
Dec 04, 2009
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inwardgranny
i'm taking both 40mg of predisone in the morning and 20mg of hydrocortisone at night. is there a reason why you can't take them both. i also have meniere ear which the predisone helps and my seg rate is high so i might have some other autoimmune disease. but i know this is working for me. i'm not swelling anymore taking them both.
Jun 28, 2010
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rumpled
Well, you can take them both but it is very very hard on the body. Your 40mg is pretty high - as said before, 5mg is enough to shut down and replace adrenal function. Pred lasts 24-36 hours, so I am not sure why your doc is making you take HC at night unless he really really does not want you to sleep? A person who takes HC to live, like me, avoids taking HC anywhere in the afternoon so that they can sleep - the body needs to have a period of time off steroids to repair muscle, bones, etc.
I would get a dexa scan and monitor your bones.
DEXA SCAN ...
Usually pred is prescribed in the case of diseases like arthritis, ms, asthma, etc. where you need anti-inflammatory action to last. As you do not appear to be developing Cushing's symptoms, you must be *using* the steroid but many of the effects may be hidden in your eyes, bones and muscles.
Jun 28, 2010
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mk549
I was diagnosed with adrenal insufficiency and a ruptured pituatiary tumor early this spring. I feel very weak if I take anything less than 40 mg. of cortisol. Is this comparable what other take -- noting that I do have chronic pain from the tumor which may elevate my need?
Jul 13, 2010
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rumpled
Pain is not usually treated with HC unless the source is inflammatory (ie arthritis) so... taking 40mg may be giving you the steroid *boost* and in turn, wrecking your body's bones and muscles...
Have you taken a UFC or other testing to see how your body is using that steroid? You do the urinary free cortisol test on meds, to see how you are - and you should be in mid-range.
Jul 14, 2010
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Lucy96
Im on 5mg of pred for sarcordosis of the lungs ive been slowly coming off the pred for 2 and half years and have every side effect. My endo wants me to start taking 15mg of HC in the morning and 5mg at 5:00pm....to see if i feel better and have more energy...
As of now i sleep about 12-14 hours a day. Just wanted to know if this is a good idea or just stick to the pred...my lung doc said i could come down to 2.5mg of pred and see how i do.
Just want some input...Thanks
Aug 16, 2010
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rumpled
You are taking pred for your lungs so you have a reason for it, however, it seems that your side effects show that your body is not liking it.
If you can cut to 2.5mg pred, think of this, pred takes about 4 hours to kick in, and can last up to 36 hours (hence the side effects), HC kicks in pretty much right away, but only lasts about 6 hours. That 5pm dose may or may not, depending on you, cause sleep issues. Most endos advise dosing no later than 2 or 3pm but some people need a 2.5mg HC at night to sleep. It happens.
You may be sleeping so much as you may have a case of steroid-induced Cushing's - it causes fatigue. It does a number in the muscles and has a lot of other hidden side effects. 5mg =20mg HC, so to just take the 2.5 pred would put you under a suppressive dose, and force your adrenals to work, if it in fact they could, and if you have been on steroids a long time, well, they may not. That could be a dangerous situation. To get out of the Cushing's, you need to drop the pred, but it is going to hurt to get back and force yourself back, as you know, weaning bites.
So that is food for thought... I cannot make the decision - you could alternate days since pred lasts so long though... that is one way to help wean. You may also need more HC in the wean since the pred lasts longer, it acts like more. Just ideas.
Aug 17, 2010
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allmymarbles
I am confused. It was prednisone that gave me adrenal fatigue.
Aug 28, 2010
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rumpled
Yes - alas, pred can give AI, but in Lucy (and maybe you, I can't recall your history) she was taking the pred for a lung disorder.
Some docs give pred, dex or HC to treat AI - it can depend on the patient, the doc, the activity or the other diseases the person has...
If a person takes large doses of a suppressive corticosteroid... some lose the adrenals, some don't. Bodies are weird that way.
Aug 29, 2010
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allmymarbles
I had a lung disorder too. It seems to me that the endocrine system is still little understood.
Aug 29, 2010
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Brucergoldberg
Hey Rumpled,
This is a really old post but i am starting to explore taking predisone and possibly hydrocortisone because i am having a hard time tolerating the levothyroxine.
I wanted to ask you, people speak of 2.5 mg and 1mg of predisone. That is a tiny tiny amount, correct? The smallest dose that could be prescribed is .10. So how does someone take 2.5? 1?
I feel like my adrenals are kicking in and producing excess adrenaline in response to the levo, or hypothyroidism..
bruce
Nov 13, 2010
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rumpled
I am not a proponent of the "thyroid and adrenal" thing - I take both medications, have for years... the only stuff I have read on it is not on medical sites but other and I respectfully just don't follow those thoughts. If you need thyroid, you need, it but you may be on the wrong dose?
If you feel buzzed, then perhaps, the the pred is giving you a buzz of cortisol. If you look up a corticosteroid calculator, you will see that pred lasts a long time - it also takes about 4 hours to kick in. So when you take pred, you basically stack doses. Pred is not given in emergencies for that reason.
I don't know anything about any adrenaline response - I would think it is racing heart for too much thyroid or too much pred.
I would guess to take 2.5 you take a whole bunch of pills or do a bunch of cutting of larger pills.
Nov 14, 2010
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tgcieri
Hi Lucy....I too have Sarcoidosis...have for 20 years...also have Gastro Paresis, Chrones and I get granulomas in my sinues (had 5 surgeries already and number 6 is being scheduled)... (auto immune diseases love me). I found when they took me off the Prednisone and put me on the Hydrocortisone....everyone was ignoring my other issues. I have a "smoking cough" (never smoked) that has been lingering for 3 months now....I have Chronic Bronchitus (COPD) so my pulmonary doctor is not happy....they just put me back on prednisone...and stopped the Hydrocortisone...until I am through the Prednisone regiment. I feel better on Prednisone! I do watch what I eat all the time...I find on the Hydrocortisone I am ALWAYS looking to put something in mouth....hold water weight...and gained a lot more weight than I did on Prednisone. I am going to talk to my endo doctor about staying on Prednisone...they have to consider all my other issues....I don't think the Hydrocortisone is a fixer for Sarcoidosis....we need something that stays in the body...I was told the Hydrocortisone is only a 4 hour fix per pill...which means (for me) on 3 a day....I am only being covered for 12 of the 24 hours..... hope this gives you some answers...everyone is different...but you probably need to talk to your pulmonary and endo doctors...or have them talk to each other....good luck!
Mar 23, 2012
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Bones1970
I have Adrenal insuffiency and Chronic Cluster headaches. I am no longer on HC or Pred and now my headaches flare up longer and more often. The treatment calls for 10ltr of oxygen and 60 mg of prednisone. Prednisone caused my Arenal problems. Confused with 24/7/365 headaches
Oct 26, 2012
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rumpled
Are you still on the pred? It is confusing since you say you are not, but your treatment calls for it? If you stopped and you have AI, you probably have a headache as you are in a LOW - in other words you need some sort of replacement for cortisol.
I get massive headaches when I don't have enough cortisol.
Oct 27, 2012
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lesnmike
From what we were told by our endocrinologist, if you are taking the medication for Addison's Disease (or adrenal insufficiancy) you will not get the side affects of weight gain,moon face, etc. because your body is so low on the cortisol that by taking the oral meds is bringing your body up to normal, when these side affects ususlly happen, it is from an overamount of cortisol in your body, such as taking it for asthma, arthritis, etc.
Sep 13, 2013
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